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  4. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate  (Synonyms: MOG (35-55) (acetate))

目录号: HY-P1240B 纯度: 99.82%
COA 产品使用指南

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55)) acetate 是中枢神经鞘的一个次要成分。Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate 有致脑炎活性,诱导 T 细胞增殖。Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate 诱导 Th1 细胞因子反应以及相对高水平的 IgG 抗体产生。Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate 引发复发缓解性神经系统疾病,伴有广泛的斑块样脱髓鞘。

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Custom Peptide Synthesis

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate Chemical Structure

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate Chemical Structure

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2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 价格 是否有货 数量
1 mg ¥700
In-stock
5 mg ¥1900
In-stock
10 mg ¥3050
In-stock
50 mg   询价  
100 mg   询价  

* Please select Quantity before adding items.

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Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55)) acetate is a minor component of CNS myelin. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate has encephalitogenic activity and induces T cell proliferative. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate induces Th1 cytokine response as well as relatively high levels of IgG antibodies. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate produces a relapsing-remitting neurological disease with extensive plaque-like demyelination[1][2][3].

体外研究
(In Vitro)

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate (0-50 μg/mL;72 小时;淋巴结细胞) 诱导 T 细胞增殖并分泌 Th1 细胞因子,包括 IFN-γ、TNF-α、IL-10、IL-4 和 IL-5。Myelin Oligodendrocyte Glycoprotein Peptide (35-55),mouse, rat acetate 可增加 IgG 的水平[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate (200 μg (0.2 mL);腹腔注射;一次,持续 38 天) 在 HLA-DR2 (DRB1*1501) 小鼠中具有脑炎活性[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: HLA-DR2 (DRB1*1501) mice[1]
Dosage: 200 μg (0.2 mL)
Administration: Intraperitoneal injection; once, for 38 days
Result: Resulted in paralysis of both hind and forelimbs.
分子量

2642.00

Formula

C120H181N35O31S

性状

固体

颜色

White to off-white

Sequence Shortening

MEVGWYRSPFSRVVHLYRNGK

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

溶解性数据
In Vitro: 

H2O 中的溶解度 : 100 mg/mL (37.85 mM; 超声助溶)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.3785 mL 1.8925 mL 3.7850 mL
5 mM 0.0757 mL 0.3785 mL 0.7570 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

* 备注:如您选择水作为储备液,请稀释至工作液后,再用 0.22 μm 的滤膜过滤除菌后使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
该产品水溶性佳,请具体参考实测 水 / PBS / Saline 中的溶解度数据。
您所需的储备液浓度超过该产品的实测溶解度,如有需要,请与 MCE 中国技术支持联系。
纯度 & 产品资料
参考文献

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.3785 mL 1.8925 mL 3.7850 mL 9.4625 mL
5 mM 0.0757 mL 0.3785 mL 0.7570 mL 1.8925 mL
10 mM 0.0379 mL 0.1893 mL 0.3785 mL 0.9463 mL
15 mM 0.0252 mL 0.1262 mL 0.2523 mL 0.6308 mL
20 mM 0.0189 mL 0.0946 mL 0.1893 mL 0.4731 mL
25 mM 0.0151 mL 0.0757 mL 0.1514 mL 0.3785 mL
30 mM 0.0126 mL 0.0631 mL 0.1262 mL 0.3154 mL

* 备注:如您选择水作为储备液,请稀释至工作液后,再用 0.22 μm 的滤膜过滤除菌后使用。

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate
目录号:
HY-P1240B
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