1. Others Metabolic Enzyme/Protease
  2. Isotope-Labeled Compounds Drug Metabolite
  3. N-Acetyl mesalazine-d3

N-Acetyl mesalazine-d3  (Synonyms: N-Acetyl-5-aminosalicylic acid-d3; N-Acetyl-ASA-d3)

目录号: HY-66008S 纯度: ≥98.0%
COA 产品使用指南 技术支持

N-Acetyl mesalazine-d3 (N-Acetyl-5-aminosalicylic acid-d3) 是 N-Acetyl mesalazine (HY-66008) 的氘代物。N-Acetyl mesalazine (N-Acetyl-5-aminosalicylic acid) 是 5-Aminosalicylic Acid (HY-15027) 的主要肠道代谢产物,可作为评估 5-Aminosalicylic Acid (HY-15027) 疗效的生物标志物。N-Acetyl mesalazine 可清除自由基、减少 DNA 碱基羟基化以及改善黏膜炎症。N-Acetyl mesalazine 可用于结肠炎和结肠癌等疾病的研究。

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N-Acetyl mesalazine-d<sub>3</sub> Chemical Structure

N-Acetyl mesalazine-d3 Chemical Structure

CAS No. : 93968-79-7

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Other Forms of N-Acetyl mesalazine-d3:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

N-Acetyl mesalazine-d3 (N-Acetyl-5-aminosalicylic acid-d3) is the deuterium labeled N-Acetyl mesalazine (HY-66008). N-Acetyl mesalazine (N-Acetyl-5-aminosalicylic acid) is the primary intestinal metabolite of 5-Aminosalicylic Acid (HY-15027) and serves as a biomarker for evaluating the efficacy of 5-Aminosalicylic Acid (HY-15027). N-Acetyl mesalazine can scavenge free radicals, reduce DNA base hydroxylation, and ameliorate mucosal inflammation. N-Acetyl mesalazine can be used in the study of diseases such as colitis and colon cancer[1].

体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

198.19

Formula

C9H6D3NO4

CAS 号
非标记 CAS
性状

固体

颜色

White to off-white

中文名称

5-乙酰氨基水杨酸-d3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: ≥98.0%

参考文献
  • 摩尔计算器

  • 稀释计算器

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
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目录号:
HY-66008S
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