1. Immunology/Inflammation
  2. Interleukin Related
  3. NI-1201

NI-1201  (Synonyms: TZLS-501)

目录号: HY-P991602
技术支持

NI-1201 是一种单克隆抗体,靶向人类 IL-6R 序列中 25F10 识别的小鼠表位。NI-1201 可抑制 IL-6 顺式和反式信号传导。NI-1201 靶向 hIL-6R 的 IIb 位点。NI-1201 可抑制 gp130 与 IL-6R 的结合。

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NI-1201

NI-1201 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

NI-1201 is a monoclonal antibody that targets, in the human IL-6R sequence, the epitope recognized by 25F10 for mice. NI-1201 inhibits both IL-6 cis- and trans-signaling. NI-1201 targets site IIb of hIL-6R. NI-1201 inhibits gp130 binding to IL-6R[1].

反应种属

Human

IC50 & Target

IL-6Ra/CD126

基因 ID

3570  [NCBI]

Accession
靶点

IL-6Ra/CD126

应用

ELISA, FACS, Functional assay

偶联物

Unconjugated

复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
NI-1201
目录号:
HY-P991602
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