2. Immunology/Inflammation NF-κB Metabolic Enzyme/Protease
  3. NADPH Oxidase Reactive Oxygen Species (ROS)
  4. NOX5-IN-2

NOX5-IN-2 (Compound 17) 是一种选择性 NADPH 氧化酶 5 (NOX5) 抑制剂，IC50 为 0.70 μM。NOX5-IN-2 显著抑制 freestyle293 细胞中 NOX5 依赖性的 ROS 产生(EC50：1.8 μM)。NOX5-IN-2 可用于 NOX 相关疾病的研究，例如心血管、癌症和神经炎症。

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NOX5-IN-2 Chemical Structure

NOX5-IN-2 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
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NOX5-IN-2 相关抗体

Top Publications Citing Use of Products

查看 NADPH Oxidase 亚型特异性产品:

查看所有亚型
NOX1 NOX2 NOX4 NOX5 DUOX1

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

NOX5-IN-2 (Compound 17) is a selective NADPH oxidase 5 (NOX5) inhibitor with an IC50s of 0.70  μM. NOX5-IN-2 significantly inhibits NOX5-dependent production of ROS in freestyle293 cells (EC50: 1.8  μM). NOX5-IN-2 can be used for NOXs related diseases research, such as cardiovascular, cancer and neuroinflammation[1].

IC50 & Target[1]

NOX5

0.70 μM (IC50)

NOX1

>100 μM (IC50)

NOX2

>100 μM (IC50)

NOX4

>100 μM (IC50)

DUOX1

>15 μM (IC50)

分子量

394.84

Formula

C18H11ClN6OS
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

NOX5-IN-2 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NOX5-IN-2NADPH OxidaseReactive Oxygen Species (ROS)NOXInhibitorsNADPH oxidase 5NOX5ROSFreestyle293 cellsCardiovascularCancerNeuroinflammationInhibitorinhibitorinhibit

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目录号：
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