2. Epigenetics
  3. DNA Methyltransferase
  4. O6BTG-C8-αGlu

O6BTG-C8-αGlu 是一种 O6-甲基鸟嘌呤-DNA甲基转移酶 (MGMT) 抑制剂，IC50 为 0.45 μM。在 0.1 μM 的浓度下，O6BTG-C8-αGlu 能够完全抑制 HeLaS3 细胞 MGMT，长期应用高剂量 (高达 20 μM) 时，也不具有细胞毒性。O6BTG-C8-αGlu 适用于 MGMT 相关的癌症疾病研究。

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O6BTG-C8-αGlu Chemical Structure

O6BTG-C8-αGlu Chemical Structure

CAS No. : 793035-88-8

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O6BTG-C8-αGlu 相关抗体

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生物活性

O6BTG-C8-αGlu is an O6-methylguanine-DNA methyltransferase (MGMT) inhibitor with an IC50 of 0.45 μM. At a concentration of 0.1 μM, O6BTG-C8-αGlu can completely inhibit MGMT in HeLaS3 cells. Even when applied chronically at high doses (up to 20 μM), it does not exhibit cytotoxicity. O6BTG-C8-αGlu is suitable for research on MGMT-related cancer diseases[1].

分子量

616.53

Formula

C24H34BrN5O7S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

O6BTG-C8-αGlu 相关分类

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Keywords:

O6BTG-C8-αGlu793035-88-8DNA MethyltransferaseDNMTsDNA MTasesInhibitorinhibitorinhibit

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