2. Anti-infection
  3. Bacterial
  4. Omodenbamab

Omodenbamab  (Synonyms: 514-G3)

目录号: HY-P99770 纯度: 96.77%
COA

摩尔计算器

Omodenbamab 是一种抗 SpA (葡萄球菌蛋白 A) 人源单克隆抗体，KD 值为 0.0467 nM。 Omodenbamab 通过靶向细胞壁部分蛋白 A (SpA) 来规避关键的 S. aureus 逃避机制。Omodenbamab 可用于 S. aureus 血流感染的研究。

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Omodenbamab Chemical Structure

Omodenbamab Chemical Structure

CAS No. : 2241724-48-9

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规格 价格 是否有货 数量
1 mg ￥3000
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5 mg ￥7800
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Omodenbamab 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Omodenbamab is an anti-SpA (Staphylococcal protein A) human monoclonal antibody with a KD value of 0.0467 nM. Omodenbamab circumvents a key S. aureus evasion mechanism by targeting the cell wall moiety Protein A (SpA). Omodenbamab can be used in research of S. aureus bloodstream infection[1].

体外研究
(In Vitro)

Omodenbamab (514-G3) 与 S. aureus 结合并使 Fc 区暴露以供 FcγR1A 受体结合[1]。 Omodenbamab (10 μg/mL; 30 min, 1.5 hr, and 2.5 hr) 支持人类血细胞对 S. aureus 的调理吞噬作用[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Omodenbamab 相关抗体:
体内研究
(In Vivo)

Omodenbamab (514-G3; 2.5 mg/mice and 10 mg/mice; i.v.) 在菌血症模型中保护小鼠免受 MRSA 的致死攻击[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Balb/C mice with MRSA in a bacteremia model[1]
Dosage: 2.5 mg/mice and 10 mg/mice
Administration: Intravenous injection
Result: Increased mouse Balb/C mice with MRSA in a bacteremia model survival.
Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

纯度: 96.77%

COA (150 KB)

抗体抑制剂使用指南 (1152 KB)
参考文献

Omodenbamab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Omodenbamab2241724-48-9514-G3BacterialS. aureusStaphylococcal protein Abloodstream infectionInhibitorinhibitorinhibit

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