1. Anti-infection
  2. RABV
  3. Ormutivimab

Ormutivimab  (Synonyms: NM57; rhRIG)

目录号: HY-P99792

Ormutivimab (rhRIG) 是一种重组人单克隆抗体,靶向狂犬病病毒。Ormutivimab 可中和多种狂犬病病毒株。Ormutivimab 对狂犬病暴露后预防 (PEP) 模型具有强大的效力。

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Ormutivimab Chemical Structure

Ormutivimab Chemical Structure

CAS No. : 2449086-91-1

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Ormutivimab (rhRIG) is a recombinant human monoclonal antibody, targeting rabies virus. Ormutivimab neutralizes a variety of rabies virus strains. Ormutivimab exhibits potent potency against rabies post-exposure prophylaxis (PEP) model[1][2].

(In Vivo)

Ormutivimab (20 IU/kg;肌肉注射;单剂量) 保护比格犬免受 RABV BD06 的致命攻击[1]
Ormutivimab (20 IU/kg、100 IU/kg;肌注;单剂量) 保护受攻击的 Kunming 小鼠免受各种狂犬病病毒的侵害[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Balb/c mice challenge model with rabies virus[1]
Dosage: 20 IU/kg, 100 IU/kg
Administration: Intramuscular injection; single dose after 4 hr after infection
Result: Protected mice from rabies CVS-24 and GZ-1 isolates at a comparable rate (90%) to that of HRIG, human antirabies immune globulin.

Please store the product under the recommended conditions in the Certificate of Analysis.

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Ormutivimab 相关分类

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.


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