2. 天然产物
  3. 植物
  4. 毛茛科
  5. Delphinium staphisagria L.
  6. Paeonoside

Paeonoside 是一种在 P. suffruticosa 中鉴定的生物活性化合物，可以促进成骨细胞分化中的伤口愈合和迁移。Paeonoside 也被报道具有一定的抗糖尿病活性，可防止脓毒症引起的致死性。

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Paeonoside Chemical Structure

Paeonoside Chemical Structure

CAS No. : 20309-70-0

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Paeonoside 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Paeonoside is a bioactive compound identified in P. suffruticosa that promotes wound healing and migration in osteoblast differentiation. Paeonoside has also been reported to have some antidiabetic activity and may prevent sepsis-induced lethality[1].

体外研究
(In Vitro)

Paeonoside (PASI) (0.1-100 μM, 24 h) has no cytotoxic effect on pro-osteoblasts of MC3T3-E1 cells[1].
Paeonoside (PASI) (1-30 μM, 24 h) can significantly restore wound areas and promote cell migration in a dose-dependent manner during the induction of preosteoblast of MC3T3-E1 cells differentiation using osteogenic supplement (OS) medium. In parallel, PASI promotes alkaline phosphatase (ALP) staining and its activity in a dose-dependent manner[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Paeonoside 相关抗体:

Western Blot Analysis[1]

Cell Line: Pro-osteoblasts of MC3T3-E1 cells
Concentration: 1-10 μM
Incubation Time: 24 h
Result: Increased the expression of BMP2 and Wnt3a, stimulated Smad1/5/8 phosphorylation, GSK3β phosphorylation and β-linked protein expression as well as upregulated RUNX2 expression.
分子量

328.31

Formula

C15H20O8
CAS 号
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

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  • Do most proteins show cross-species activity?

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Keywords:

Paeonoside20309-70-0Otherswound healingmigrationosteoblast differentiationantidiabeticsepsis-induced lethalityInhibitorinhibitorinhibit

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