2. Epigenetics
  3. Epigenetic Reader Domain
  4. PBRM1-BD2-IN-7

PBRM1-BD2-IN-7 是一种选择性和细胞活性的 PBRM1 溴化域抑制剂。PBRM1-BD2-IN-7 对 PBRM1-BD2 具有抑制活性，IC50 值为 0.29 μM。PBRM1-BD2-IN-7 可用于癌症的研究。

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PBRM1-BD2-IN-7 Chemical Structure

PBRM1-BD2-IN-7 Chemical Structure

CAS No. : 2819989-68-7

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规格 价格 是否有货 数量
1 mg ￥2205
1 周
5 mg   询价  
10 mg   询价  

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PBRM1-BD2-IN-7 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PBRM1-BD2-IN-7 is a selective and cell-active polybromo-1 (PBRM1) bromodomain inhibitor. PBRM1-BD2-IN-7 has inhibitory activity for PBRM1-BD2 with an IC50 value of 0.29 μM. PBRM1-BD2-IN-7 can be used for the research of cancer[1].

IC50 & Target

IC50: 0.29 μM (PBRM1-BD2)[1].
体外研究
(In Vitro)

PBRM1-BD2-IN-7 (0, 0.1, 1, and 10 μM; 5 days) selectively inhibit growth of a PBRM1-dependent prostate cancer cell line[1].
PBRM1-BD2-IN-7 has inhibitory activity for PBRM1-BD2 with IC50 value of 0.29 μM[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

PBRM1-BD2-IN-7 相关抗体:

Cell Viability Assay[1]

Cell Line: Human prostate cell lines LNCaP, PC3, and RWPE-1
Concentration: 0, 0.1, 1, and 10 μM
Incubation Time: 5 days
Result: Inhibited LNCaP growth at higher concentrations.
分子量

286.76

Formula

C16H15ClN2O
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

PBRM1-BD2-IN-7 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PBRM1-BD2-IN-72819989-68-7Epigenetic Reader Domainpolybromo-1 (PBRM1)bromodomainbinding affinityinhibitorycancerInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-151534
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