2. GPCR/G Protein
  3. GLP Receptor GCGR
  4. Pemvidutide

Pemvidutide (ALT-801) 是一种 GLP-1R/GCGR 双重激动剂，可导致体重、肝脏脂肪和血清脂质的显著降低。Pemvidutide 可用于非酒精性脂肪性肝炎 (NASH) 和肥胖症的研究。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Custom Peptide Synthesis

Pemvidutide Chemical Structure

Pemvidutide Chemical Structure

CAS No. : 2538014-94-5

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Pemvidutide 的其他形式现货产品:

Customer Review

Other Forms of Pemvidutide:

Pemvidutide 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Pemvidutide (ALT-801) is a GLP-1R/GCGR dual agonist, shows striking reductions in body weight, liver fat and serum lipids. Pemvidutide can be used in non-alcoholic steatohepatitis (NASH) and obesity research[1].

体内研究
(In Vivo)

Pemvidutide (subcutaneous injection; 5 or 10 nmol/kg; once daily; 12 w) treatment improves NASH (nonalcoholic steatohepatitis) outcomes in vivo[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: C57BL6/J mice (with biopsy-confirmed NAS score after 29 weeks on a HFFC diet)[1]
Dosage: 5 or 10 nmol/kg
Administration: Subcutaneous injection; 5 or 10 nmol/kg; once daily; 12 weeks
Result: Lowered hepatic lipids, liver weight, biomarkers of liver injury (plasma ALT and AST), the inflammation marker galactin-3, the fibrosis marker Col1a1, and the NAS score.
分子量

3873.35

同用名

ALT-801

Formula

C182H275N39O54
CAS 号
Sequence

His-{Aib}-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Glu--{Lys(N6-(1-O-(17-Carboxyheptadecyl)-D-Glucopyranuronoyl))}-Ala-Ala-Lys-Glu-Phe-Ile-Gln-Trp-Leu-Leu-Gln-Thr-NH2 (Lactam bridge: Glu-16;Lys-20)
Sequence Shortening

H-{Aib}-QGTFTSDYSKYLDE-{Lys(N6-(1-O-(17-Carboxyheptadecyl)-D-Glucopyranuronoyl))}-AAKEFIQWLLQT-NH2 (Lactam bridge: Glu-16;Lys-20)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Pemvidutide 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pemvidutide2538014-94-5ALT-801ALT801ALT 801GLP ReceptorGCGRGlucagon Receptorbody weightliver fatserum lipidnon-alcoholic steatohepatitisNASHobesityInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Pemvidutide
目录号：
HY-145632
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z