1. Antibody-drug Conjugate/ADC Related
  2. Radionuclide-Drug Conjugates (RDCs)
  3. Pentetreotide

Pentetreotide 是 Octreotide (HY-P0036) 的 DTPA 共轭物。Pentetreotide 是一种铟标记的生长抑素类似物,可用于核医学成像。Pentetreotide 与生长抑素受体闪烁显像可有效观察神经内分泌肿瘤及其转移。

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Custom Peptide Synthesis

Pentetreotide

Pentetreotide Chemical Structure

CAS No. : 138661-02-6

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查看 Radionuclide-Drug Conjugates (RDCs) 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Pentetreotide is a diethylenetriaminopentaacetic (DTPA) conjugate of Octreotide (HY-P0036). Pentetreotide is an indium-labelled somatostatin analog and can be uesd to nuclear medicine imaging. Somatostatin receptor scintigraphy with Pentetreotide is effective in visualizing neuroendocrine tumors, and its metastasis[1][2].

IC50 & Target[1]

RDC Peptide

 

体外研究
(In Vitro)

与正常组织相比,神经内分泌肿瘤的生长抑素受体数量增加。目前已知有五种亚型。采用111In-Pentetreotide 进行生长抑素受体闪烁显像可与其中两种亚型结合,并可有效显影神经内分泌肿瘤及其转移灶[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

1394.57

Formula

C63H87N13O19S2

CAS 号
Sequence

Gly-{D-Phe}-Cys-Phe-{D-Trp}-Lys-Thr-Cys-Thr (Disulfide bridge: Cys3-Cys8)

Sequence Shortening

G{D-Phe}CF{D-Trp}KTCT (Disulfide bridge: Cys3-Cys8)

中文名称

喷曲肽

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Pentetreotide
目录号:
HY-P2022
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