1. 天然产物
  2. 植物 生物碱 酚类
  3. 樟科 异喹啉类生物碱 多酚类
  4. 乌药
  5. (+)-Coclaurine

(+)-Coclaurine  (Synonyms: (+)-(R)-Coclaurine; (R)-Coclaurine; d-Coclaurine)

目录号: HY-N2550
产品使用指南 技术支持

(+)-Coclaurine ((+)-(R)-Coclaurine),是一种四氢异喹啉生物碱,从多种植物来源中分离出来,具有抗衰老活性。

在相同的摩尔浓度下,化合物盐形式与游离形式有相同的生物活性,但盐形式 (+)-Coclaurine hydrochloride 通常具有更好的水溶性和稳定性。

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(+)-Coclaurine

(+)-Coclaurine Chemical Structure

CAS No. : 2196-60-3

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规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

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(+)-Coclaurine 的其他形式现货产品:

Customer Review

Other Forms of (+)-Coclaurine:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(+)-Coclaurine ((+)-(R)-Coclaurine), benzyltetrahydroisoquinoline alkaloid isolated from a variety of plant sources. (+)-Coclaurine has anti-aging activity[1][2].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
H9 EC50
2.8 μM
Compound: 121
Antiviral activity against HIV1 3B infected in H9 cells assessed as inhibition of viral replication by p24 antigen ELISA
Antiviral activity against HIV1 3B infected in H9 cells assessed as inhibition of viral replication by p24 antigen ELISA
[PMID: 20187635]
体内研究
(In Vivo)

An intracerebroventricular injection of (+)-Coclaurine (d-Coclaurine; 50 μg) produces a slight increase in 3,4-dihydroxyphenylacetic acid level and a significant increase in homovanillic acid level in the mouse striatum. (+)-Coclaurine blocks postsynaptic but not presynaptic dopamine receptors in the mouse striatum[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

285.34

Formula

C17H19NO3

CAS 号
中文名称

(+)-乌药碱;乌药碱

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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HY-N2550
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