2. JAK/STAT Signaling Protein Tyrosine Kinase/RTK
  3. EGFR
  4. Ponezumab

Ponezumab  (Synonyms: PF-04360365; RN 1219)

目录号: HY-P99216 纯度: 95.00%
COA

摩尔计算器

Ponezumab (PF-04360365) 是一种人源化抗淀粉样蛋白 IgG2 单克隆抗体。Ponezumab 可降低中枢神经系统的 Aβ 水平，并改善小鼠在各种学习和记忆模型中的表现。Ponezumab 可用于阿尔茨海默症的研究。

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Ponezumab Chemical Structure

Ponezumab Chemical Structure

CAS No. : 1178862-65-1

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规格 价格 是否有货 数量
1 mg ￥6200
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Ponezumab 相关抗体

Top Publications Citing Use of Products

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EGFR/ErbB1/HER1 ErbB2/HER2 ErbB3/HER3 ErbB4/HER4

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Ponezumab (PF-04360365) is a humanised anti-amyloid IgG2 monoclonal antibody. Ponezumab reduces Aβ levels in the central nervous system and improves performance in mice in various models of learning and memory. Ponezumab can be used in study of Alzheimer's disease[1].

IC50 & Target

IgG2[1].
Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Ponezumab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ponezumab1178862-65-1PF-04360365 RN 1219PF04360365PF 04360365RN1219RN 1219RN-1219EGFREpidermal growth factor receptorErbB-1HER1Aβalzheimer's diseaseInhibitorinhibitorinhibit

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