1. 重组蛋白
  2. CAR-T related Proteins CD Antigens
  3. CD138/Syndecan-1 B Cell CD Proteins Stem Cell CD Proteins Epithelial cell CD Proteins Endothelial cell CD Proteins
  4. CD138/Syndecan-1 CD138/Syndecan-1
  5. Syndecan-1/CD138 蛋白, Human (HEK293, Fc)

Syndecan-1/CD138 蛋白, Human (HEK293, Fc)

目录号: HY-P77851
COA 产品使用指南

Syndecan-1/CD138 蛋白是一种细胞表面蛋白聚糖,通过硫酸乙酰肝素和硫酸软骨素将细胞骨架与间质基质连接起来。它通过 SDCBP 和 PDCD6IP 调节外泌体生物合成。Syndecan-1/CD138 蛋白通过牙细胞中的 MSX1 途径诱导其自身表达,并与 CDCP1 和 TIAM1 相互作用。它还与 MDK 相互作用,参与多种细胞过程。Syndecan-1/CD138 蛋白, Human (HEK293, Fc) 是重组的 Syndecan-1/CD138 蛋白,由 HEK293 表达,带有 C-hFc 标签。Syndecan-1/CD138 蛋白, Human (HEK293, Fc) 全长 232 个氨基酸,分子量为 70-100 kDa。

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重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 价格 是否有货 数量
20 μg ¥1580 In-stock
50 μg ¥3480 In-stock
100 μg ¥5900 询价
> 100 μg   询价  

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描述

Syndecan-1/CD138 Protein, a cell surface proteoglycan, connects the cytoskeleton to the interstitial matrix with heparan sulfate and chondroitin sulfate. It regulates exosome biogenesis with SDCBP and PDCD6IP. Syndecan-1/CD138 Protein induces its own expression through an MSX1 pathway in dental cells and interacts with CDCP1 and TIAM1. It also interacts with MDK, participating in diverse cellular processes. Syndecan-1/CD138 Protein, Human (HEK293, Fc) is the recombinant human-derived Syndecan-1/CD138 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Syndecan-1/CD138 Protein, Human (HEK293, Fc) is 232 a.a., with molecular weight of 70-100 kDa.

研究背景

Syndecan-1/CD138 蛋白是一种细胞表面蛋白聚糖,其特征在于存在硫酸乙酰肝素和硫酸软骨素,使其能够发挥连接细胞骨架与间质基质的作用。它与 SDCBP 和 PDCD6IP 合作调节外泌体生物发生。此外,Syndecan-1/CD138 蛋白不仅能够在牙齿间充质细胞中诱导自身表达,而且还能够通过 MSX1 介导的途径在邻近的牙齿上皮细胞中诱导表达。它与 CDCP1 和 TIAM1 相互作用,特别是分别通过其 C 端和 TIAM1 的 PDZ 域。此外,Syndecan-1/CD138 蛋白与 MDK 相互作用,促进其参与各种细胞过程。

生物活性

Measured by its binding ability in a functional ELISA. When immobilized Human Syndecan-1,hFc Tag at 1μg/ml (100μl/Well), can bind Biotinylated Anti-Syndecan-1 Antibody, hFc Tag and the EC50 is 18 ng/mL.

种属

Human

表达系统

HEK293

标签

C-hFc

蛋白编号

P18827 (Q23-G254)

基因 ID
蛋白结构
N-term
CD138 (Q23-G254)
Accession # P18827
hFc
C-term
同用名
Syndecan-1; SYND1; CD138; SDC1; SDC; SDC1
分子量

70-100 kDa

纯度

Greater than 95% as determined by Tris-Bis PAGE

性状

无菌粉末.

组分

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Normally 8% trehalose is added as protectant before lyophilization.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Syndecan-1/CD138 Protein, Human (HEK293, Fc)
目录号:
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