1. GPCR/G Protein Neuronal Signaling Membrane Transporter/Ion Channel
  2. Cannabinoid Receptor TRP Channel
  3. (R)-Methanandamide

(R)-Methanandamide  (Synonyms: AM-356)

目录号: HY-101389
产品使用指南

(R)-Methanandamide (AM-356),内源性大麻素配体 Anandamide 的类似物,是一种有效的 CB1 激动剂,Ki 为 20 nM。(R)-Methanandamide 也能激活 TRPV1 受体。

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(R)-Methanandamide Chemical Structure

(R)-Methanandamide Chemical Structure

CAS No. : 157182-49-5

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(R)-Methanandamide (AM-356), an analog of the endocannabinoid ligand Anandamide, is a potent CB1 agonist with a Ki of 20 nM. (R)-Methanandamide also activates vanilloid (TRPV1) receptors[1][2].

IC50 & Target[1][2]

CB1

20 nM (Ki)

TRPV1

 

体外研究
(In Vitro)

The endogenous cannabinoid (R)-Methanandamide exerts differential anti- and pronociceptive effects by activating both cannabinoid (CB1) and vanilloid (TRPV1) receptors of nociceptive primary afferents[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

361.56

Formula

C23H39NO2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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(R)-Methanandamide
目录号:
HY-101389
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