2. Neuronal Signaling
  3. Monoamine Oxidase
  4. (R)-Pirlindole mesylate

(R)-Pirlindole mesylate 是一种选择性、可逆性的单胺氧化酶A (MAO-A) 抑制剂，其对 MAO-A 的 IC50 为 0.43 μM，优于对 MAO-B 的抑制作用。(R)-Pirlindole mesylate 具有抗抑郁活性。(R)-Pirlindole mesylate 显著缩短了行为小鼠模型中强迫游泳试验的静止时间，并抑制了Reserpine (HY-N0480) 诱发的眼睑下垂。((R)-Pirlindole mesylate 可用于抑郁症研究。

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(R)-Pirlindole mesylate

(R)-Pirlindole mesylate Chemical Structure

CAS No. : 1821379-62-7

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(R)-Pirlindole mesylate 相关抗体

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查看 Monoamine Oxidase 亚型特异性产品:

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MAO-A MAO-B

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(R)-Pirlindole mesylate is selective and reversible a Monoamine oxidase A (MAO-A) inhibitor with an IC50 of 0.43  μM for MAO-A over MAO-B. (R)-Pirlindole mesylate has an antidepressant activity. (R)-Pirlindole mesylate significantly decreases immobility time of the forced swim test and inhibits Reserpine (HY-N0480)-induced palpebral ptosis in behavioural mice models. (R)-Pirlindole mesylate can be used for depression research[1].

IC50 & Target[1]

MAO-A

0.43 μM (IC50)

分子量

322.42

Formula

C16H22N2O3S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

(R)-Pirlindole mesylate 相关分类

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  • 稀释计算器

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Keywords:

(R)-Pirlindole1821379-62-7Monoamine OxidaseMAOInhibitorMonoamine oxidase AMAO-AAntidepressantBehavioural mice modelsDepressioninhibitorinhibit

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