1. NF-κB
  2. IKK
  3. (Rac)-BAY-985

(Rac)-BAY-985 

目录号: HY-133117A
产品使用指南

(Rac)-BAY-985 (Compound Example 100.01) 是一种高效的,ATP 竞争性的,选择性 TBK1 抑制剂, IC50 为 1.5 nM。具有抗肿瘤功效。

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(Rac)-BAY-985 Chemical Structure

(Rac)-BAY-985 Chemical Structure

CAS No. : 2101925-20-4

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Description

(Rac)-BAY-985 (Compound Example 100.01) is a potent, ATP-competitive and selective TBK1 inhibitor with an IC50 of 1.5 nM. Antitumor efficacy[1].

IC50 & Target[1]

TBK1

1.5 nM (IC50)

Molecular Weight

553.58

Formula

C₂₇H₃₀F₃N₉O

CAS No.

2101925-20-4

SMILES

O=C(N1CCN(C(C2=CC(NC3=NC4=CC=C(C5=NC=NC(N(C)C)=C5)C=C4N3)=NC=C2)C)CC1)CC(F)(F)F

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

(Rac)-BAY-985IKKIκB kinaseI kappa B kinaseTBK1Inhibitorinhibitorinhibit

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产品名称:
(Rac)-BAY-985
目录号:
HY-133117A
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