2. Apoptosis
  3. TNF Receptor
  4. RG-7212 (RO5458640)

RG-7212 (RO5458640)  (Synonyms: RO5458640)

目录号: HY-P990657 纯度: 99.62%
COA 技术支持

RG-7212 (RO5458640) 是 CHO 表达的人源抗体，靶向 TNFSF12/TWEAK。RG-7212 (RO5458640) 带有 huIgG1 型重链和 huκ 型轻链，其预测的分子量 (MW) 为 146.02 kDa。RG-7212 (RO5458640) 的同型对照可参考 Human IgG1 kappa, Isotype Control (HY-P99001)。

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规格 价格 是否有货 数量
1 mg ￥3000
In-stock
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RG-7212 (RO5458640) 相关抗体

Top Publications Citing Use of Products

查看 TNF Receptor 亚型特异性产品:

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TNFRSF1A/CD120a TNFRSF3/CD18 TNFRSF4 TNFRSF5/CD40 TNFRSF6/Fas/CD95 TNFRSF7/CD27 TNFRSF8/CD30 TNFRSF9/4-1BB/CD137 TNFRSF12A/TWEAK TNFRSF16/NGF Receptor/CD271 TNFRSF18/GITR/CD357

  • 生物活性

  • 纯度 & 产品资料

生物活性

RG-7212 (RO5458640) is a human-derived antibody expressed in CHO cells, targeting TNFSF12/TWEAK. RG-7212 (RO5458640) has a huIgG1 type heavy chain and a huκ type light chain, with a predicted molecular weight (MW) of 146.02 kDa. The isotype control for RG-7212 (RO5458640) can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).

同型

Human IgG1 kappa
推荐同型对照抗体
反应种属

Human
IC50 & Target

TWEAK

 

Clinical Trial
基因 ID

8742  [NCBI]

Accession
应用

ELISA, FACS, Functional assay
偶联物

Unconjugated
复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.
分子量

146.02 kDa

性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
  • Immobilized Human TNFSF12/TWEAK, Fc tag can bind RG-7212 (RO5458640). The EC50 for this effect is 108.7 ng/mL.
  • Flow Cytometry analysis of A431 cells labelling ERBB1/EGFR/HER1 (red) with RG-7212 (RO5458640) (anti-ERBB1/EGFR/HER1) (HY-P990657). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Human IgG1 kappa (HY-P99001). Black-Unlabelled control, cells without incubation with primary antibody.
纯度 & 产品资料

RG-7212 (RO5458640) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RG-7212 (RO5458640)RO5458640RO 5458640RO-5458640TNF ReceptorTumor Necrosis Factor ReceptorTNFRHuman AntibodyTNFSF12/TWEAK AntibodyInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-P990657
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