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Rubropunctamine 

目录号: HY-N6643
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Rubropunctamine 是一种从红曲霉发酵米(红霉米)提取物中分离出来的红色氮杂酮类色素。Rubropunctamine 具有抗炎症活性。

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Rubropunctamine Chemical Structure

Rubropunctamine Chemical Structure

CAS No. : 514-66-9

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Description

Rubropunctamine is a red azaphilone pigment isolated from the extracts of Monascus pilosus-fermented rice (red-mold rice). Rubropunctamine has anti-inflammation activities[1][2].

In Vitro

Rubropunctamine (0.32-32 nM; 48 h) inhibits Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA), with an IC50 of 433 mol ratio/32 pmol TPA[1].
Rubropunctamine (1 h) exhibits moderate scavenging activity (inhibitory ratio (IR)=1.5) against NO generation by (±)-(E)-methyl-2[(E)-hydroxy-imino]-5-nitro-6-methoxy-3-hexemide (NOR 1) in normal human hepato cells[1].

In Vivo

Rubropunctamine inhibits TPA-induced inflammation in mice, with an ID50 of 0.32 mg/ear[1].

Molecular Weight

353.41

Formula

C₂₁H₂₃NO₄

CAS No.

514-66-9

中文名称

潘红胺

SMILES

O=C1O[C@]2(C)C(C=C3C(C2=O)=CNC(/C=C/C)=C3)=C1C(CCCCC)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

RubropunctamineOthersredpigmentMonascuspilosusred-moldriceanti-inflammationInhibitorinhibitorinhibit

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产品名称:
Rubropunctamine
目录号:
HY-N6643
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