2. GPCR/G Protein
  3. Endothelin Receptor
  4. Sarafotoxin S6a

Sarafotoxin S6a 是一种 Sarafotoxin 类似物，是一种内皮素受体 (endothelin receptor ) 激动剂，具有与 Endothelin-3 (HY-P0204) 相似的 ETA/ETB 选择性。Sarafotoxin S6a 诱导猪冠状动脉的 EC50 值为 7.5 nM。

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Custom Peptide Synthesis

Sarafotoxin S6a Chemical Structure

Sarafotoxin S6a Chemical Structure

CAS No. : 126738-34-9

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规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

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Other Forms of Sarafotoxin S6a:

Sarafotoxin S6a 相关抗体

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Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Sarafotoxin S6a, a sarafotoxin analogue, is a endothelin receptor agonist and has an ETA/ETB selectivity profile similar to that of Endothelin-3 (HY-P0204). Sarafotoxin S6a elicits the pig coronary artery with an EC50 value of 7.5 nM[1].

IC50 & Target[1]

ETB

 

ETA

 

体外研究
(In Vitro)

Sarafotoxin S6a is a rather weak agonist effect in guinea-pig aorta, the eliting concentration (EC50) is 150 nM in guinea-pig aorta[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Sarafotoxin S6a 相关抗体:
分子量

2514.85

Formula

C105H156N28O34S5
CAS 号
Sequence

Cys-Ser-Cys-Lys-Asp-Met-Thr-Asp-Lys-Glu-Cys-Leu-Asn-Phe-Cys-His-Gln-Asp-Val-Ile-Trp (Disulfide bridge:Cys1-Cys15;Cys3-Cys11)
Sequence Shortening

CSCKDMTDKECLNFCHQDVIW (Disulfide bridge:Cys1-Cys15;Cys3-Cys11)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
溶解性数据

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

In Vivo:

以下溶解方案源自文献，仅供参考，建议您先取少量样品进行尝试。

  • 方案 一

    S6a is dissolved in 0.1% aqueous acetic acid and diluted in 0.9% NaCl[1].

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

Sarafotoxin S6a 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sarafotoxin S6a126738-34-9Endothelin Receptorguinea-pigaortaendothelin receptorcoronary arteryEndothelin-3Inhibitorinhibitorinhibit

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产品名称：
Sarafotoxin S6a
目录号：
HY-P1112
需求量：

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