1. Screening Libraries
  2. Anti-COVID-19 Compound Library

抗 COVID-19 化合物库 - Anti-COVID-19 Compound Library

Cat. No.: HY-L052
Library Contents: XLSX PDF SDF

新型冠状病毒给人们的健康带来严重威胁,快速开发有效治疗冠状病毒的药物迫在眉睫。利用处于临床期及上市药物进行抗冠状病毒药物的筛选可以大大缩短研发周期,另外,虚拟筛选技术在新药筛选前期也可以有效缩小筛选范围,提高筛选效率。

MCE 发挥自身虚拟筛选优势,基于 3CL 水解酶 (Mpro, PDB ID: 6LU7),S 蛋白 (Spike Glycoprotein, PDB ID: 6VSB),NSP15 (PDB ID: 6VWW), RDRP, PLPro 及人 ACE2 (人蛋白血管紧张素转换酶2) 结构对已有的上市药物库及临床化合物库,进行虚拟筛选,汇总整理出 1557 个可能具有抗新型冠状病毒活性的化合物集合,是筛选抗新型冠状病毒药物的有力工具。

我们为 MCE 抗 COVID-19 化合物库 中的所有产品提供溶液包装或粉末包装。溶液包装中,1534 个产品以 10 mM 浓度提供,18 个产品以 2 mM 浓度提供,5 个产品以 3 mg/mL 浓度提供。

溶液包装中,我们对于溶液状态稳定且溶解度不低于 10 mM 的产品,提供 10 mM 溶液;对于溶液状态稳定且溶解度介于 2~10 mM 的产品,我们提供 2 mM 溶液;对于溶液状态稳定、分子量不确定且溶解度不低于 3 mg/mL产品,我们提供 3 mg/mL 溶液。

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
Size (Pre-dissolved Solution or Solid) Price Stock
30 μL/well Solution

10 mM , 2 mM and 3 mg/mL
Pre-dissolved Solution

Get quote In-stock
50 μL/well Solution

10 mM , 2 mM and 3 mg/mL
Pre-dissolved Solution

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100 μL/well Solution

10 mM , 2 mM and 3 mg/mL
Pre-dissolved Solution

Get quote In-stock
2 × 100 μL/well Solution

10 mM , 2 mM and 3 mg/mL
Pre-dissolved Solution

Get quote In-stock

Please contact us at

sales@MedChemExpress.cn

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Description
& Advantages

•   A unique collection of 1557 compounds that may have anti-COVID-19 activity for high throughput screening (HTS) and high content screening (HCS).

•   All compounds are derived from virtual screening of approved compound library and clinical compound library based on the 3CL protease, Spike Glycoprotein and ACE2 structure.

•   A useful tool for the development of anti-COVID-19 drugs.

•   Bioactivity and safety confirmed by preclinical research and clinical trials.

•   Structurally diverse, medicinally active, and cell permeable.

•   More detailed compound information with structure, IC50, and brief introduction.

•   NMR and HPLC validated to ensure high purity and quality.

•   All compounds are in stock and continuously updated.

Product Details
Formulation:
A collection of 1557 compounds that may have anti-COVID-19 activity supplied as pre-dissolved Solutions or Solid
Solution: 1534 compounds supplied in 10 mM solution, 18 compounds supplied in 2 mM solution, 5 compounds supplied in 3 mg/mL solution.
Container:
96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Storage:
-80°C
Shipping:
Blue ice
Composition

Anti-COVID-19 Compound Library

Source: MedChem Express

Contents of Anti-COVID-19 Compound Library
Documentation

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    Anti-COVID-19 Compound Library
    目录号:
    HY-L052
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    • 96-well Plate with Peelable Foil Seal
    • 384-well Microplate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack