1. 一站式药筛
  2. 化合物库
  3. 生物活性化合物库系列
  4. 信号通路化合物库系列
  5. 抗氧化化合物库
抗氧化化合物库 - Antioxidant Compound Library

Cat. No.: HY-L037

氧化应激是由于体内活性氧与抗氧化剂失衡产生的,可以导致细胞和组织的损伤。氧化应激可诱发多种疾病的发生,包括慢性疾病及退行性疾病,以及加速身体衰老过程和引起急性病理。抗氧化剂是一类能够对抗氧化应激并减轻其对人体损伤的一类化合物,受到了生物医学研究界的极大关注。长期以来,抗氧化剂一直是治疗诸如阿尔兹海默症和癌症等多种疾病的重要药物。

MCE 抗氧化化合物库包括 1,498 种对氧化应激具有抑制作用的小分子化合物,可以用于高通量筛选和高内涵筛选。该化合物库是开发新的抗氧化剂,研究氧化应激的有用工具。

我们将在明确您的产品用途后,向符合资质的客户通过定制合成服务的方式提供 MCE 抗氧化化合物库,我们为该库中的所有产品提供溶液包装或粉末包装。溶液包装中,1,465 个产品以 10 mM 浓度提供,23 个产品以 2 mM 浓度提供,10 个产品以 3 mg/mL 浓度提供。

溶液包装中,我们对于溶液状态稳定且溶解度不低于 10 mM 的产品,提供 10 mM 溶液;对于溶液状态稳定且溶解度介于 2~10 mM 的产品,我们提供 2 mM 溶液;对于溶液状态稳定、分子量不确定且溶解度不低于 3 mg/mL产品,我们提供 3 mg/mL 溶液。

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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Compound Screening Libraries

Top Publications Citing Use of MCE Products

MCE 顾客使用化合物库产品发表的文献

  • 生物活性
  • 产品详情
  • 产品资料
  • 化合物库组成

活性描述 & 特点

Biological Activity

•   A unique collection of 1,498 compounds that act as antioxidants for high throughput screening (HTS) and high content screening (HCS).

•   Targets such as NF-κB, mTOR, Keap1-Nrf2, AMPK, Sirtuin, etc.

•   Bioactivity and safety confirmed by preclinical research and clinical trials, some compounds have been approved by FDA.

•   A useful tool to study oxidative stress.

•   More detailed compound information with structure, IC50, and other chemical & biological data.

•   NMR and HPLC validated ensure high purity.

•   All compounds are in stock and continuously updated.

产品详情

Product Details

Formulation:

A collection of 1,498 antioxidants supplied as pre-dissolved Solutions or Solid
Solution: 1,465 compounds supplied in 10 mM solution, 23 compounds supplied in 2 mM solution, 10 compounds supplied in 3 mg/mL solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage:

-80°C

Shipping:

Blue ice or dry ice

化合物库组成

Composition

NF-κB (263)

mTOR (102)

AMPK (72)

PI3K (51)

COX (45)

Akt (36)

HIV (25)

ERK (22)

PPAR (16)

MMP (14)

STAT (14)

HSV (11)

HBV (10)

JNK (10)

JAK (7)

PARP (7)

HSP (6)

CDK (5)

HCV (5)

HDAC (5)

IKK (5)

SOD (5)

Wnt (5)

AIM2 (4)

EGFR (4)

FAK (4)

PKC (4)

相关服务推荐
定制您专属的化合物库
  •  特定化合物
  •  化合物数量
  •  产品排布图
  •  浓度
  •  形式(固体或溶液)
  •  YES
联系专家定制
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack

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    产品名称:
    Antioxidant Compound Library
    目录号:
    HY-L037
    需求量: