1. 一站式药筛
  2. 化合物库
  3. 生物活性化合物库系列
  4. 根据产品结构分类
  5. 杂环化合物库
杂环化合物库 - Heterocyclic Compound Library

Cat. No.: HY-L138

杂环化合物是包含至少一个杂原子的环状有机化合物,最常见的杂原子是氮、氧和硫。杂环在生物学中很常见,具有广泛的结构,从酶辅因子到氨基酸和蛋白质。一方面,杂环是上市药物和药物化学靶标中常见的结构单位。此外,杂环也是医学化学中的一个重要结构,在维生素、天然产物和抗真菌、抗炎、抗菌、抗氧化、抗过敏、抗艾滋病毒、抗糖尿病、抗癌等生物活性分子中都有大量的杂环存在。

MCE 提供 5892 个杂环化合物,可以用于高通量筛选和高内涵筛选。MCE杂环化合物库是药物发现和开发的关键。

我们将在明确您的产品用途后,向符合资质的客户通过定制合成服务的方式提供 MCE 杂环化合物库,我们为该库中的所有产品提供溶液包装或粉末包装。溶液包装中,5790 个产品以 10 mM 浓度提供,93 个产品以 2 mM 浓度提供,9 个产品以 3 mg/mL 浓度提供。

溶液包装中,我们对于溶液状态稳定且溶解度不低于 10 mM 的产品,提供 10 mM 溶液;对于溶液状态稳定且溶解度介于 2~10 mM 的产品,我们提供 2 mM 溶液;对于溶液状态稳定、分子量不确定且溶解度不低于 3 mg/mL产品,我们提供 3 mg/mL 溶液。

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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Compound Screening Libraries

Top Publications Citing Use of MCE Products

MCE 顾客使用化合物库产品发表的文献

  • 生物活性
  • 产品详情
  • 产品资料
  • 化合物库组成

活性描述 & 特点

Biological Activity

•    A unique collection of 5892 heterocyclic compounds for high throughput screening (HTS) and high content screening (HCS).

•    A useful tool for the study of critical for drug discovery and development.

•    Target diverse, medicinally active and cell permeable.

•    Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.

•    More detailed compound information with structure, IC50, and other chemical & biological data.

•    High purity and quality validated by NMR and LC/MS.

产品详情

Product Details

Formulation:

A collection of 5892 heterocyclic compounds supplied as pre-dissolved Solutions or Solid
Solution: 5790 compounds supplied in 10 mM solution, 93 compounds supplied in 2 mM solution, 9 compounds supplied in 3 mg/mL solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage:

-80°C

Shipping:

Blue ice

化合物库组成

Composition

CDK (135)

EGFR (108)

PI3K (81)

VEGFR (73)

HIV (69)

JAK (66)

mAChR (62)

FLT3 (54)

FGFR (51)

nAChR (49)

mGluR (48)

mTOR (45)

PDGFR (45)

HCV (40)

c-Kit (39)

Src (39)

Ras (37)

Wnt (37)

iGluR (36)

HDAC (35)

Akt (33)

Btk (33)

PARP (33)

CCR (32)

ERK (31)

Raf (30)

HSP (29)

COX (27)

PPAR (27)

ROCK (27)

MMP (26)

GSK-3 (25)

CXCR (23)

HBV (21)

相关服务推荐
定制您专属的化合物库
  •  特定化合物
  •  化合物数量
  •  产品排布图
  •  浓度
  •  形式(固体或溶液)
  •  YES
联系专家定制
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack

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    产品名称:
    Heterocyclic Compound Library
    目录号:
    HY-L138
    需求量: