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拟肽化合物库 - Peptidomimetic Library

Cat. No.: HY-L033
Library Contents: XLSX PDF SDF

拟肽化合物是一类药效团在三维空间中模拟天然肽或蛋白质,并保留与生物靶标相互作用的能力,产生相同的生物效应的化合物。拟肽化合物的设计是为了规避一些天然肽自身存在的问题:如对蛋白水解作用的稳定性(活性持续时间)和较差的生物利用度,某些其他性质,如受体的选择性或效能,往往可以得到很大的改善。拟肽的设计和合成是非常重要的,因为在分子识别和信号传递中,尤其是在生命系统中,肽和蛋白-蛋白相互作用起着主导作用。因此,拟肽类化合物在新药开发中具有巨大潜力。

MCE 拟肽类化合物库包含 383 种小分子化合物,包括类肽,α-螺旋类似物,β-折叠类似物等,是药物发现中研究构效关系不可或缺的工具。

我们将在明确您的产品用途后,向符合资质的客户通过定制合成服务的方式提供 MCE 拟肽化合物库,我们为该库中的所有产品提供溶液包装或粉末包装。溶液包装中,309 个产品以 10 mM 浓度提供,6 个产品以 2 mM 浓度提供。

溶液包装中,我们对于溶液状态稳定且溶解度不低于 10 mM 的产品,提供 10 mM 溶液;对于溶液状态稳定且溶解度介于 2~10 mM 的产品,我们提供 2 mM 溶液。

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
Size (Pre-dissolved Solution or Solid) Price Stock
30 μL/well Solution

10 mM and 2 mM
Pre-dissolved Solution

Get quote In-stock
50 μL/well Solution

10 mM and 2 mM
Pre-dissolved Solution

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100 μL/well Solution

10 mM and 2 mM
Pre-dissolved Solution

Get quote In-stock
2 × 100 μL/well Solution

10 mM and 2 mM
Pre-dissolved Solution

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sales@MedChemExpress.cn

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Description
& Advantages

•   A unique collection of 383 compounds that act as substitutes for peptides in their interaction with receptors for drug discovery.

•   In contrast to natural peptides, compounds have high affinity and selectivity, high absorbent and metabolic stability and no immunogenicity.

•   Peptoid, α-helixmimetics, β-turn/sheets mimetics and compounds target protein-protein interactions are included.

•   A useful tool for the discovery of peptide-like drugs.

•   More detailed compound information with structure, IC50, and other chemical & biological data.

•   NMR and HPLC validated ensure high purity.

•   All compounds are in stock and continuously updated.

Product Details
Formulation:
A collection of 383 compounds supplied as pre-dissolved Solutions or Solid
Solution: 309 compounds supplied in 10 mM solution, 6 compounds supplied in 2 mM solution.
Container:
96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Storage:
-80°C
Shipping:
Blue ice
Documentation

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    产品名称:
    Peptidomimetic Library
    目录号:
    HY-L033
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    • 96-well Plate with Peelable Foil Seal
    • 384-well Microplate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack
    • 96-well Storage Tubes with Rack