1. Screening Libraries
  2. Macrocyclic Compound Library

大环类化合物库 - Macrocyclic Compound Library

Cat. No.: HY-L041
Library Contents: XLSX PDF SDF

大环化合物是指含有 12 元或更大环的分子,在小分子药物开发中越来越受到重视。主要原因包括:大环类化合物提供了新的化学空间,挑战新的蛋白质靶标,另外,一些大环类药物也显示出较好的药代动力学性能。大环类化合物对于比较具有挑战性的靶点的药物开发具有一定优势,特别是在调节大分子之间相互作用如蛋白蛋白相互作用方面。此外,大环化合物的大小和复杂性使其能够保证更大的空间分布的结合相互作用,从而增加结合亲和力和选择性。

MCE 提供 132 个大环类化合物,可以用于高通量筛选和高内涵筛选。MCE 大环类化合物库是新药开发的有利工具,尤其对于“难成药”靶点及蛋白互作的新药研发。

  • 96-well Plate with Peelable Foil Seal
Size (Solid) Price Stock
1 mg Get quote In-stock

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Description
& Advantages

•   A unique collection of 132 macrocyclic compounds that for drug discovery.

•   A useful tool for the discovery of "undruggable" targets such as protein-protein interactions (PPIs) inhibitors.

•   Cyclopeptides, crown ethers, calixarene and so on are included.

•   More detailed compound information with structure, IC50, and other chemical & biological data.

•   NMR and HPLC validated ensure high purity.

•   All compounds are in stock and continuously updated.

Product Details
Formulation:
A collection of 132 macrocyclic compounds supplied as Solid
Container:
96-well Storage Tubes with Rack
Storage:
-80°C
Shipping:
Blue ice
Composition

Macrocyclic Compound Library

Source: MedChem Express

Documentation

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    产品名称:
    Macrocyclic Compound Library
    目录号:
    HY-L041
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    • 96-well Plate with Peelable Foil Seal