1. Cell Cycle/DNA Damage
    Anti-infection
  2. Bacterial
    DNA/RNA Synthesis
    Antibiotic
  3. Silver sulfadiazine

Silver sulfadiazine (Synonyms: AgSD)

目录号: HY-B1497 纯度: >98.0%
产品使用指南

Silver sulfadiazine (AgSD) 是一种磺胺类抗生素,通磺胺部分 (SD-SDZ) 对细菌 (bacterial) 生长产生双重抑制作用,阻止细菌叶酸吸收和随后的 DNA 合成 (DNA synthesis)。Silver sulfadiazine 释放的银结合并破坏 DNA 结构,阻止细菌 DNA 复制。

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Silver sulfadiazine Chemical Structure

Silver sulfadiazine Chemical Structure

CAS No. : 22199-08-2

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Description

Silver sulfadiazine (AgSD), a sulfonamide antibiotic, effects a dual inhibitory action on bacterial growth by its sulfa moiety (SD-SDZ) that prevents bacterial folate absorption and subsequent DNA synthesis. The silver that is released from Silver sulfadiazine binds and disrupts the DNA structure, precluding bacterial DNA replication[1].

In Vitro

Silver sulfadiazine (AgSD) is a topical antibiotic used to the research of bacterial infection in burns[2].

Molecular Weight

357.14

Formula

C₁₀H₉AgN₄O₂S

CAS No.

22199-08-2

中文名称

磺胺嘧啶银

SMILES

NC(C=C1)=CC=C1S2(=O[Ag+][N]3=CC=C[N-]C3=N2)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

References
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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Silver sulfadiazineAgSDBacterialDNA/RNA SynthesisAntibioticbacterialinfectionburnsDNAstructuresynthesisfolateabsorptionInhibitorinhibitorinhibit

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Silver sulfadiazine
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HY-B1497
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