1. Metabolic Enzyme/Protease Autophagy Apoptosis
  2. HMG-CoA Reductase (HMGCR) Autophagy Mitophagy Apoptosis Ferroptosis
  3. Simvastatin-d6

Simvastatin-d6  (Synonyms: MK 733-d6)

目录号: HY-110231
产品使用指南

Simvastatin-d6 (MK 733-d6) 是 Simvastatin 的氘代物。Simvastatin (MK 733) 是一种竞争性的 HMG-CoA reductase 抑制剂,Ki 值为 0.2 nM。

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Simvastatin-d6 Chemical Structure

Simvastatin-d6 Chemical Structure

CAS No. : 1002347-71-8

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规格 价格 是否有货
500 μg ¥2223
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Other Forms of Simvastatin-d6:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Simvastatin-d6 (MK 733-d6) is the deuterium labeled Simvastatin. Simvastatin (MK 733) is a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

424.60

Formula

C25H32D6O5

CAS 号
非标记 CAS

79902-63-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Simvastatin-d6
目录号:
HY-110231
需求量: