2. Metabolic Enzyme/Protease
  3. Phosphodiesterase (PDE)
  4. TDP1-IN-4

TDP1-IN-4 (Compound 33) 是一种酪氨酰-DNA 磷酸二酯酶 1 (TDP1) 抑制剂，其 IC50 为 0.90 μM。TDP1-IN-4 与 Camptothecin (HY-16560) 在 SK-Mel-2 细胞中具有强协同作用，但在癌细胞 (A549、HCT-116 和 MCF-7 细胞) 和非癌性 Ges-1 细胞中无此作用。TDP1-IN-4 可用于癌症化疗和放疗研究。

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TDP1-IN-4

TDP1-IN-4 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
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Customer Review

TDP1-IN-4 相关抗体

Top Publications Citing Use of Products

查看 Phosphodiesterase (PDE) 亚型特异性产品:

查看所有亚型
PDE1 PDE2 PDE3 PDE4 PDE5 PDE6 PDE7 PDE9 PDE10 PDE11 PDE12 PDE8 Autotaxin

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

TDP1-IN-4 (Compound 33) is a Tyrosyl-DNA phosphodiesterase 1 (TDP1) inhibitor with an IC50 of 0.90  μM. TDP1-IN-4 has a strong synergistic effect with Camptothecin (HY-16560) in SK-Mel-2 cells, but not in cancer cells (A549, HCT-116 and MCF-7 cells) and non-cancerous Ges-1 cells. TDP1-IN-4 can be used for cancer chemotherapy and radiotherapy research[1].

分子量

781.98

Formula

C49H55N3O6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

TDP1-IN-4 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TDP1-IN-4Phosphodiesterase (PDE)TDP1Synergistic effectCamptothecinSK-Mel-2 cellsCancer chemotherapy and radiotherapyInhibitorinhibitorinhibit

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目录号：
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