2. Anti-infection
  3. Reverse Transcriptase HIV
  4. Tenofovir diphosphate

Tenofovir diphosphate  (Synonyms: TFV-DP)

目录号: HY-136548
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Tenofovir diphosphate 是一种抗逆转录病毒药物。Tenofovir diphosphate 是HIV 逆转录酶 DNA (Ki = 1.55 μM) 和 RNA (Ki = 0.022 μM) 的抑制剂。Tenofovir diphosphate 可用于艾滋病毒 (AIDS) 的研究。

该游离形式化合物不稳定，推荐具有相同生物学活性的稳定盐形式 Tenofovir diphosphate disodium。

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Tenofovir diphosphate Chemical Structure

Tenofovir diphosphate Chemical Structure

CAS No. : 166403-66-3

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Tenofovir diphosphate 的其他形式现货产品:

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Other Forms of Tenofovir diphosphate:

Tenofovir diphosphate 相关抗体

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MCE 顾客使用本产品发表的 1 篇科研文献

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HIV HIV-1 HIV-2

  • 生物活性

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生物活性

Tenofovir diphosphate is an antiretroviral agent. Tenofovir diphosphate is an inhibitor of HIV reverse transcriptase DNA (Ki = 1.55 μM) and RNA (Ki = 0.022 μM). Tenofovir diphosphate can be used for the research of AIDS[1].

IC50 & Target

DNA polymerases; HIV-1 reverse transcriptase[1]
体外研究
(In Vitro)

Tenofovir diphosphate acts as an inhibitor of DNA pol. Tenofovir-diphosphate is a weak inhibitor of DNA polymerases (pol) α, δ, and , with values for the Ki for PMPApp (PMPAppKi) relative to the Km for dATP (dATPKm) of 10.2, 10.2, and 15.6, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Tenofovir diphosphate 相关抗体:
分子量

447.17

Formula

C9H16N5O10P3
CAS 号
中文名称

替诺福韦二磷酸酯
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Tenofovir diphosphate 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tenofovir diphosphate166403-66-3TFV-DP替诺福韦二磷酸酯Reverse TranscriptaseHIVHuman immunodeficiency virusDNApolymerasessubstrateHIV-1reversetranscriptaseInhibitorinhibitorinhibit

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