1. Anti-infection
  2. Reverse Transcriptase
  3. Tenofovir diphosphate triethylamine

Tenofovir diphosphate triethylamine  (Synonyms: TFV-DP triethylamine)

目录号: HY-136548A
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Tenofovir diphosphate triethylamine (TFV-DP triethylamine) 是一种 ATP 竞争性的 DNA 聚合酶 (DNA polymerases) 抑制剂,且是 1 型 HIV (HIV-1) 逆转录酶 (RT) 的底物。

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Tenofovir diphosphate triethylamine Chemical Structure

Tenofovir diphosphate triethylamine Chemical Structure

CAS No. : 2122333-63-3

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Tenofovir diphosphate triethylamine 的其他形式现货产品:

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Tenofovir diphosphate triethylamine (TFV-DP triethylamine) is a competitive DNA polymerases inhibitor (with respect to dATP) and a substrate of HIV type 1 (HIV-1) reverse transcriptase (RT)[1].

体外研究
(In Vitro)

Tenofovir diphosphate acts as an inhibitor of DNA pol. Tenofovir-diphosphate is a weak inhibitor of DNA polymerases (pol) α, δ, and ɛ, with values for the Ki for PMPApp (PMPAppKi) relative to the Km for dATP (dATPKm) of 10.2, 10.2, and 15.6, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

548.36

Formula

C15H31N6O10P3

CAS 号
性状

固体

颜色

Light yellow to yellow

中文名称

替诺福韦二磷酸酯三乙胺

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

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