1. Anti-infection
  2. Reverse Transcriptase
  3. Tenofovir diphosphate triethylamine

Tenofovir diphosphate triethylamine  (Synonyms: TFV-DP triethylamine)

目录号: HY-136548A
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Tenofovir diphosphate triethylamine (TFV-DP triethylamine) 是一种 ATP 竞争性的 DNA 聚合酶 (DNA polymerases) 抑制剂,且是 1 型 HIV (HIV-1) 逆转录酶 (RT) 的底物。

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Tenofovir diphosphate triethylamine Chemical Structure

Tenofovir diphosphate triethylamine Chemical Structure

CAS No. : 2122333-63-3

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Tenofovir diphosphate triethylamine 的其他形式现货产品:

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MCE 顾客使用本产品发表的 1 篇科研文献

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Tenofovir diphosphate triethylamine (TFV-DP triethylamine) is a competitive DNA polymerases inhibitor (with respect to dATP) and a substrate of HIV type 1 (HIV-1) reverse transcriptase (RT)[1].

体外研究
(In Vitro)

Tenofovir diphosphate acts as an inhibitor of DNA pol. Tenofovir-diphosphate is a weak inhibitor of DNA polymerases (pol) α, δ, and , with values for the Ki for PMPApp (PMPAppKi) relative to the Km for dATP (dATPKm) of 10.2, 10.2, and 15.6, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

548.36

同用名

TFV-DP triethylamine

Formula

C15H31N6O10P3

CAS 号
性状

固体

颜色

Light yellow to yellow

中文名称

替诺福韦二磷酸酯三乙胺

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

纯度 & 产品资料
参考文献

Tenofovir diphosphate triethylamine 相关分类

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