1. Antibody-drug Conjugate/ADC Related PROTAC
  2. ADC Linker PROTAC Linkers
  3. Tetraethylene glycol monotosylate

Tetraethylene glycol monotosylate  (Synonyms: Tos-PEG4)

目录号: HY-41541
产品使用指南

Tetraethylene glycol monotosylate 是一种可降解 (cleavable) 的基于酰基腙的 ADC linker,用于合成抗体偶联活性分子 (ADCs)。Tetraethylene glycol monotosylate 也可用作 PROTAC 的 Linker,可用于 PROTAC 的合成。

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Tetraethylene glycol monotosylate Chemical Structure

Tetraethylene glycol monotosylate Chemical Structure

CAS No. : 77544-60-6

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  • 生物活性

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生物活性

Tetraethylene glycol monotosylate is a cleavable and acylhydrazone-based ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Tetraethylene glycol monotosylate also can be used as a PROTAC linker that can be used in the synthesis of PROTACs.

IC50 & Target[1]

Cleavable Linker

 

PEGs

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

348.41

Formula

C15H24O7S

CAS 号
性状

粘稠液体

颜色

Colorless to light yellow

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献

Tetraethylene glycol monotosylate 相关分类

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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产品名称:
Tetraethylene glycol monotosylate
目录号:
HY-41541
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