1. Immunology/Inflammation
  2. Interleukin Related
  3. TQC2938

TQC2938 是一种靶向刺激因子-2 (ST2) 的人源化 IgG2 单克隆抗体抑制剂。TQC2938 抑制 ST2/IL-33 信号通路,降低下游 Th2 细胞因子 (如 IL-4、IL-5 和 IL-13) 以及嗜酸性粒细胞和其他炎症细胞的水平。TQC2938 可用于哮喘等炎症性疾病研究。

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TQC2938

TQC2938 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

TQC2938 is a humanized IgG2 monoclonal antibody inhibitor targeting Stimulation-2 (ST2). TQC2938 inhibits the ST2/IL-33 signaling pathway, reduces the level of downstream Th2 cytokines (such as IL-4, IL-5, and IL-13) and eosinophils as well as other inflammatory cells. TQC2938 can be used for inflammatory diseases like asthma research[1].

同型

Human IgG2 kappa

推荐同型对照抗体
反应种属

Human

IC50 & Target[1]

ST2

 

基因 ID

9173  [NCBI]

Accession
靶点

IL-1RL1/ST2/IL-33R

应用

ELISA, FACS, Functional assay

偶联物

Unconjugated

复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

产品名称:
TQC2938
目录号:
HY-P991633
需求量: