2. Cell Cycle/DNA Damage Cytoskeleton
  3. Microtubule/Tubulin
  4. Tubulin polymerization-IN-32

Tubulin polymerization-IN-32 是一种微管蛋白 (tubulin) 聚合抑制剂。Tubulin polymerization-IN-32 抑制癌细胞增殖。Tubulin polymerization-IN-32 可用于淋巴瘤等癌症的研究。

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Tubulin polymerization-IN-32 Chemical Structure

Tubulin polymerization-IN-32 Chemical Structure

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Tubulin polymerization-IN-32 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Tubulin polymerization-IN-32 is a tubulin polymerization inhibitor. Tubulin polymerization-IN-32 inhibits cancer cell proliferation. Tubulin polymerization-IN-32 can be used in the research of cancers like lymphomas[1].

IC50 & Target

Tubulin polymerization[1]
体外研究
(In Vitro)

Tubulin polymerization-IN-32 (compound 14k) shows antiproliferative activity against cancer cell lines of the NCI panel, reaching GI50 values of 0.03-85.8 μM[1].
Tubulin polymerization-IN-32 (compound 14k, 72 h) inhibits lymphoma cells growth with IC50s of 1.4-2.0 μΜ[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Tubulin polymerization-IN-32 相关抗体:

Cell Proliferation Assay[1]

Cell Line: VL51, MINO, HBL1, SU-DHL-10 cells.
Concentration: 0-10 μΜ
Incubation Time: 72 h
Result: Inhibited cell proliferation to 79.7%, 41.3%, 70.1%, 59% at 1 μΜ, respectively.
IC50s: 1.8, 1.4, 1.7, 2.0 μΜ, respectively.
分子量

518.56

Formula

C29H30N2O7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Tubulin polymerization-IN-32 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tubulin polymerization-IN-32Microtubule/TubulinAntitubulinlymphomacancerVL51MINOHBL1Inhibitorinhibitorinhibit

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产品名称：
Tubulin polymerization-IN-32
目录号：
HY-151393
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