1. GPCR/G Protein Neuronal Signaling
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  3. [Tyr22] Calcitonin Gene Related Peptide, (22-37), rat

[Tyr22] Calcitonin Gene Related Peptide, (22-37), rat 

目录号: HY-P3689 纯度: 99.89%
COA 产品使用指南

[Tyr22] Calcitonin Gene Related Peptide, (22-37), rat 是一种大鼠降钙素基因相关肽 (CGRP) 的 22-37 片段,靶向 CGRP 受体和腺苷酸环化酶。降钙素 (calcitonin) 主要由甲状腺 C 细胞产生,而 CGRP 则分泌并储存在神经系统中。

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Custom Peptide Synthesis

[Tyr22] Calcitonin Gene Related Peptide, (22-37), rat Chemical Structure

[Tyr22] Calcitonin Gene Related Peptide, (22-37), rat Chemical Structure

CAS No. : 198277-54-2

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5 mg ¥2080
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10 mg ¥3540
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Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

[Tyr22] Calcitonin Gene Related Peptide, (22-37), rat is a fragments 22-37 of rat calcitonin gene related peptide (CGRP), targeting CGRP receptor and adenylate cyclase. Calcitonin is mainly produced by thyroid C cells while CGRP is secreted and stored in the nervous system[1].

体外研究
(In Vitro)

Calcitonin Gene Related Peptide (CGRP) in humans, exists in two forms: CGRP alpha (α-CGRP or CGRP I), and CGRP beta (β-CGRP or CGRP II)[2].
[Tyr22] Calcitonin Gene Related Peptide, (22-37), rat shows the receptor binding affinity mainly depending on the carboxyterminal end while the ability to stimulate adenylate cyclase (AC) enzyme mainly depending on the aminoterminal end[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

1785.95

Formula

C82H120N20O25

CAS 号
性状

固体

颜色

White to off-white

Sequence

Tyr-Val-Lys-Asp-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Glu-Ala-Phe-NH2

Sequence Shortening

YVKDNFVPTNVGSEAF-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
In Vitro: 

DMSO 中的溶解度 : 100 mg/mL (55.99 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响,请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.5599 mL 2.7996 mL 5.5993 mL
5 mM 0.1120 mL 0.5599 mL 1.1199 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

[Tyr22] Calcitonin Gene Related Peptide, (22-37), rat 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.5599 mL 2.7996 mL 5.5993 mL 13.9982 mL
5 mM 0.1120 mL 0.5599 mL 1.1199 mL 2.7996 mL
10 mM 0.0560 mL 0.2800 mL 0.5599 mL 1.3998 mL
15 mM 0.0373 mL 0.1866 mL 0.3733 mL 0.9332 mL
20 mM 0.0280 mL 0.1400 mL 0.2800 mL 0.6999 mL
25 mM 0.0224 mL 0.1120 mL 0.2240 mL 0.5599 mL
30 mM 0.0187 mL 0.0933 mL 0.1866 mL 0.4666 mL
40 mM 0.0140 mL 0.0700 mL 0.1400 mL 0.3500 mL
50 mM 0.0112 mL 0.0560 mL 0.1120 mL 0.2800 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
[Tyr22] Calcitonin Gene Related Peptide, (22-37), rat
目录号:
HY-P3689
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