2. Cell Cycle/DNA Damage Anti-infection Cytoskeleton
  3. Antibiotic Microtubule/Tubulin
  4. Vincristine

Vincristine  (Synonyms: Leurocristine; NSC-67574; 22-Oxovincaleukoblastine)

目录号: HY-N0488A
产品使用指南 技术支持

Vincristine (Leurocristine) 是一种微管去稳剂。Vincristine 与微管蛋白结合，抑制微管的形成，从而抑制癌细胞的有丝分裂。Vincristine 用于研究血液肿瘤，如白血病和淋巴瘤，以及儿童肉瘤。

该游离形式化合物不稳定，推荐具有相同生物学活性的稳定盐形式 Vincristine sulfate。

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Vincristine

Vincristine Chemical Structure

CAS No. : 57-22-7

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Vincristine 的其他形式现货产品:

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Vincristine 相关抗体

Top Publications Citing Use of Products

MCE 顾客使用本产品发表的 59 篇科研文献

WB

    Vincristine purchased from MCE. Usage Cited in: Int J Biol Macromol. 2019 Jan 30;128:574-582.  [Abstract]

    SGC7901/DDP or SGC7901/VCR cells are transfectedwith si-Con or si-ERK, and transfection efficiency is evaluated by western blot assay at 48 h post transfection.

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    • 生物活性

    • 纯度 & 产品资料

    • 参考文献

    生物活性

    Vincristine (Leurocristine) is a microtubule-destabilizing agent (MDA). Vincristine binds to tubulin and inhibits the formation of microtubules, thereby inhibiting mitosis of the cancer cell. Vincristine is used to research hematologic cancers, such as leukemia and lymphoma, and childhood sarcomas[1][2].

    Clinical Trial
    分子量

    824.96

    Formula

    C46H56N4O10
    CAS 号
    中文名称

    长春新碱
    结构分类
    初始来源
    运输条件

    Room temperature in continental US; may vary elsewhere.
    储存方式

    Please store the product under the recommended conditions in the Certificate of Analysis.
    纯度 & 产品资料
    参考文献

    Vincristine 相关分类

    • 摩尔计算器

    • 稀释计算器

    The molarity calculator equation

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    质量   浓度   体积   分子量 *
    = × ×

    The dilution calculator equation

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
    × = ×
    C1   V1   C2   V2
    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Vincristine57-22-7Leurocristine NSC-67574 22-Oxovincaleukoblastine长春新碱NSC67574NSC 67574NSC-67574AntibioticMicrotubule/TubulinInhibitorinhibitorinhibit

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