2. Immunology/Inflammation
  3. Cyclic GMP-AMP Synthase
  4. XL-3156

XL-3156 是一种强效、选择性和跨物种的 cGAS 抑制剂。XL-3156 可同时占据变构和正构位点，通过稳定激活环的闭合构象抑制 cGAS 与 DNA 的相互作用及相分离。XL-3156 可用于自身免疫病和炎症等疾病的研究。

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XL-3156 Chemical Structure

XL-3156 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
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250 mg   询价  

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Customer Review

XL-3156 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

XL-3156 is a potent, selective, and cross-species cGAS inhibitor. XL-3156 can simultaneously occupy both allosteric and orthosteric sites, and inhibit the interaction and phase separation between cGAS and DNA by stabilizing the closed conformation of the activation loop. XL-3156 can be used in the research of autoimmune diseases, inflammatory conditions and other diseases[1].

分子量

517.54

Formula

C28H23N9O2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

XL-3156 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

XL-3156XL3156XL 3156Cyclic GMP-AMP SynthasecGASHEK-293RAW-ISGL929THP-1 DualTHP1-Lucia ISGmiceInhibitorinhibitorinhibit

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产品名称：
XL-3156
目录号：
HY-174801
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