1. Others Immunology/Inflammation
  2. Isotope-Labeled Compounds COX
  3. 2-Hydroxy Ibuprofen-d6

2-Hydroxy Ibuprofen-d6  (Synonyms: 2-羟基布洛芬-d6; (±)-2-Hydroxy Ibuprofen-d6)

目录号: HY-126121S
产品使用指南

2-Hydroxy Ibuprofen-d6 是 2-Hydroxy Ibuprofen 的氘代物。2-Hydroxy Ibuprofen 是 Ibuprofen 的一种代谢产物。Ibuprofen 是 COX-1COX-2 的抑制剂,IC50 值分别为 13 μM 和 370 μM,具有抗炎的活性。

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2-Hydroxy Ibuprofen-d<sub>6</sub> Chemical Structure

2-Hydroxy Ibuprofen-d6 Chemical Structure

CAS No. : 1217055-71-4

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Other Forms of 2-Hydroxy Ibuprofen-d6:

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

2-Hydroxy Ibuprofen-d6 is the deuterium labeled 2-Hydroxy Ibuprofen. 2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

228.32

Formula

C13H12D6O3

CAS 号
中文名称

2-羟基布洛芬-d6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

2-Hydroxy Ibuprofen-d6 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
2-Hydroxy Ibuprofen-d6
目录号:
HY-126121S
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