2. Others Membrane Transporter/Ion Channel Metabolic Enzyme/Protease NF-κB Immunology/Inflammation
  3. Isotope-Labeled Compounds Na+/K+ ATPase Mitochondrial Metabolism Reactive Oxygen Species (ROS)
  4. 3-Methylglutaric acid-d4

3-Methylglutaric acid-d4  (Synonyms: 3-甲基戊二酸-d4)

目录号: HY-113410S
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3-Methylglutaric acid-d4 是 3-Methylglutaric acid (HY-113410) 的氘代物。 3-Methylglutaric acid 是一种非选择性线粒体功能抑制剂及 Na+, K+-ATP 酶抑制剂，对大鼠脑皮层突触体 Na+, K+-ATP 酶的抑制率达 30%。3-Methylglutaric acid 能诱导活性氧 (ROS) 生成，从而引发氧化损伤，抑制线粒体氧化还原电位和细胞膜的离子泵功能。3-Methylglutaric acid 可用于研究代谢性疾病的神经病理机制，及氧化应激介导的神经元损伤在神经退行性病变中的作用。

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3-Methylglutaric acid-d<sub>4</sub> Chemical Structure

3-Methylglutaric acid-d4 Chemical Structure

CAS No. : 1219798-68-1

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3-Methylglutaric acid-d4 相关抗体

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  • 生物活性

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生物活性

3-Methylglutaric acid-d4 is the deuterium labeled 3-Methylglutaric acid (HY-113410). 3-Methylglutaric acid is a non-selective inhibitor of mitochondrial function and Na+, K+-ATPase, with an inhibition rate of 30% on rat cortical synaptosomal Na+, K+-ATPase. 3-Methylglutaric acid can induce reactive oxygen species (ROS) generation, thereby causing oxidative damage and inhibiting mitochondrial redox potential and ion pump function of cell membranes. 3-Methylglutaric acid can be used to study the neuropathological mechanisms of metabolic diseases and the role of oxidative stress-mediated neuronal damage in neurodegeneration[1][2][3][4][5].

分子量

150.17

同用名

3-甲基戊二酸-d4

Formula

C6H6D4O4
CAS 号
非标记 CAS
中文名称

3-甲基戊二酸-d4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

3-Methylglutaric acid-d4 相关分类

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Keywords:

3-Methylglutaric acid-d41219798-68-13-甲基戊二酸-d4Isotope-Labeled CompoundsNa+/K+ ATPaseMitochondrial MetabolismReactive Oxygen Species (ROS)Sodium potassium pumpInhibitorinhibitorinhibit

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