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  3. 3-Phosphoglyceric acid

3-Phosphoglyceric acid  (Synonyms: 3-磷酸甘油酸)

目录号: HY-113491
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3-Phosphoglyceric acid 是一种糖酵解和卡尔文循环中的代谢中间体。3-Phosphoglyceric acid 可参与肺泡巨噬细胞的表观遗传调控。

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3-Phosphoglyceric acid Chemical Structure

3-Phosphoglyceric acid Chemical Structure

CAS No. : 820-11-1

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Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

3-Phosphoglyceric acid is a metabolic intermediate in both glycolysis and the Calvin cycle. 3-Phosphoglyceric acid is involved in alveolar macrophage epigenetic regulation.

IC50 & Target

Human Endogenous Metabolite

 

体外研究
(In Vitro)

3-Phosphoglyceric acid (400 µM; 24 hours; BMDMs) treatment enhances Spp1 transcription in VHL-deficient macrophages, and the reduced H3K4me3 modification is also reversed[1].
3-Phosphoglyceric treatment significantly augmentes gene expression as well as H3K4me3 deposition of Spp1 in IL-4-stimulated macrophages[1].
In yeast, 3-Phosphoglyceric acid acts as a metabolic checkpoint for the formation of a multicomponent enzyme complex including serine metabolic enzymes and pyruvate kinase isoform 2 (PKM2) homologue, which senses both serine metabolism and glycolysis and regulates H3K4 methylation and histone phosphorylation[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

RT-PCR[1]

Cell Line: Bone marrow-derived macrophages (BMDMs)
Concentration: 400 µM
Incubation Time: 24 hours
Result: Enhanced Spp1 transcription in VHL-deficient macrophages, and the reduced H3K4me3 modification was also reversed.
分子量

186.06

Formula

C3H7O7P

CAS 号
中文名称

3-磷酸甘油酸

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

3-Phosphoglyceric acid 相关分类

  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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3-Phosphoglyceric acid
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HY-113491
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