1. Anti-infection
  2. HCV
  3. Cyclophilin inhibitor 1

Cyclophilin inhibitor 1 是一种有效、可口服的亲环素 A (cyclophilin A) 抑制剂,Kd 值为 5 nM,具有抗 HCV 活性,对 HCV 2a 的 EC50 值为 98 nM。

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Cyclophilin inhibitor 1 Chemical Structure

Cyclophilin inhibitor 1 Chemical Structure

CAS No. : 1509904-96-4

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Cyclophilin inhibitor 1 is a potent and orally bioavailable cyclophilin A inhibitor, with a Kd of 5 nM, shows effective anti-HCV activity, with an EC50 of 98 nM for HCV 2a[1].

IC50 & Target

Kd: 5 nM (Cyclophilin A)[1]
EC50: 98 nM (HCV 2a)[1]

体外研究
(In Vitro)

Cyclophilin inhibitor 1 (Compound 3) inhibits HCV 2a activity, with an EC50 of 98 nM[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

593.67

Formula

C31H39N5O7

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Cyclophilin inhibitor 1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Cyclophilin inhibitor 1
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HY-112712
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