2. GPCR/G Protein Neuronal Signaling
  3. Dopamine Receptor
  4. Acetophenazine

Acetophenazine 是吩噻嗪衍生物，是一种抗精神病化合物。Acetophenazine 主要阻断大脑中多巴胺 D2 受体 (dopamine D2 receptors)。Acetophenazine 可用于精神分裂症、焦虑抑郁等精神障碍的研究。

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Acetophenazine Chemical Structure

Acetophenazine Chemical Structure

CAS No. : 2751-68-0

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Other Forms of Acetophenazine:

Acetophenazine 相关抗体

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Dopamine Receptor D1 Receptor D2 Receptor D3 Receptor D4 Receptor D5 Receptor

  • 生物活性

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生物活性

Acetophenazine, a phenothiazine derivative, is an antipsychotic agent. Acetophenazine primarily blocks dopamine D2 receptors in the brain. Acetophenazine can be used for researching psychotic disorders such as schizophrenia and anxious depression[1][2].

IC50 & Target[1]

D2 Receptor

 

体内研究
(In Vivo)

Acetophenazine (2.4 mg/kg; i.h.; single dosage) significantly prolongs the time lapse from the first fight to submission and the actual fighting time to submission in mice[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: C57BL mice (10-12 weeks)[3]
Dosage: 2.4 mg/kg
Administration: i.h.; single dosage
Result: Significantly prolonged the time lapse from the first fight to submission and the actual fighting time to submission.
分子量

411.56

Formula

C23H29N3O2S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Acetophenazine 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Acetophenazine2751-68-0Dopamine ReceptorPhenothiazineantipsychoticpsychotic disordersschizophreniaanxious depressionInhibitorinhibitorinhibit

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