1. GPCR/G Protein Neuronal Signaling Immunology/Inflammation
  2. Histamine Receptor
  3. Alimemazine

Alimemazine  (Synonyms: Trimeprazine)

目录号: HY-12752
产品使用指南

Alimemazine 是通常用作止痒剂的吩噻嗪衍生物,也是血凝素 (HA)- 受体的拮抗剂。Alimemazine (Trimeprazine) 是也是针对组胺H1受体 (H1R) 和其他 GPCR 的部分激动剂。Alimemazine 具有抗血清素、抗痉挛和止吐作用。

在相同的摩尔浓度下,化合物盐形式与游离形式有相同的生物活性,但盐形式 Alimemazine hemitartrate 通常具有更好的水溶性和稳定性。

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Alimemazine Chemical Structure

Alimemazine Chemical Structure

CAS No. : 84-96-8

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Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Alimemazine is a phenothiazine derivative that is generally used as an antipruritic agent and also a hemagglutinin (HA)-receptor antagonist.Alimemazine (Trimeprazine) is also acts as a partial agonist against the histamine H1 receptor (H1R) and other GPCRs. Alimemazine displays antiserotonin, antispasmodic, and antiemetic properties[1][2].

IC50 & Target

HA receptor[1]

分子量

298.45

Formula

C18H22N2S

CAS 号
中文名称

阿利马嗪

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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