2. Cell Cycle/DNA Damage Metabolic Enzyme/Protease
  3. HSP
  4. Alvespimycin TFA

Alvespimycin TFA  (Synonyms: 阿螺旋霉素三氟乙酸盐)

目录号: HY-10389A 纯度: 98.97%
COA 产品使用指南 技术支持

Alvespimycin (17-DMAG) TFA 是一种有效的 Hsp90 抑制剂，结合到 Hsp90，EC50 为 62 ± 29 nM。

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Alvespimycin TFA Chemical Structure

Alvespimycin TFA Chemical Structure

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规格 价格 是否有货 数量
5 mg ￥900
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10 mg ￥1440
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25 mg ￥2880
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50 mg ￥4320
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Customer Review

Other Forms of Alvespimycin TFA:

Alvespimycin TFA 相关抗体

Top Publications Citing Use of Products

    Alvespimycin TFA purchased from MCE. Usage Cited in: Theranostics. 2020 Jul 9;10(18):8415-8429.  [Abstract]

    Western blot analysis of three proteins of interest in astrocytes treated with the Alvespimycin (17DMAG) for 24 h. Alvespimycin treatment increases EAAT2 and Hsp70 levels in a dose-dependent manner.

    Alvespimycin TFA purchased from MCE. Usage Cited in: Friedrich-Alexander University Erlangen-Nuremberg. 2016 Sep 14.

    pJAK2 and JAK2 expression upon TGFβ stimulation and JAK inhibitors incubation. pJAK2 and JAK2 expression in healthy human fibroblasts after stimulation with TGFβ for 3 days and incubation with TG101209, 17-DMAG or Ruxolitinib.

    查看 HSP 亚型特异性产品:

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    HSP40 HSP70 HSP90 HSP105 HSF1 HSP HSPA5

    • 生物活性

    • 纯度 & 产品资料

    • 参考文献

    生物活性

    Alvespimycin (17-DMAG) TFA is a potent inhibitor of Hsp90, binding to Hsp90 with an EC50 of 62 ± 29 nM[1].

    分子量

    730.77

    同用名

    阿螺旋霉素三氟乙酸盐

    Formula

    C34H49F3N4O10
    性状

    固体

    颜色

    Pale purple to purple

    中文名称

    阿螺旋霉素三氟乙酸盐
    运输条件

    Room temperature in continental US; may vary elsewhere.
    储存方式

    -20°C, sealed storage, away from moisture and light

    *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

    纯度 & 产品资料
    参考文献

    Alvespimycin TFA 相关分类

    • 摩尔计算器

    • 稀释计算器

    The molarity calculator equation

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    质量   浓度   体积   分子量 *
    = × ×

    The dilution calculator equation

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
    × = ×
    C1   V1   C2   V2
    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Alvespimycin阿螺旋霉素三氟乙酸盐HSPHeat shock proteinsInhibitorinhibitorinhibit

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    目录号：
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