2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. GABA Receptor
  4. Anisatin

Anisatin  (Synonyms: 莽草毒素)

目录号: HY-N9506 纯度: ≥98.0%
COA 产品使用指南

摩尔计算器

Anisatin 从一种日本植物 Illicium anisatum) 种子中分离出来的一种有毒物质，是一种类苦毒素的非竞争性 b>GABA 抗剂。Anisatin 以浓度依赖性方式抑制 GABA 诱导的电流，EC50 约为 1.10 μM。

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Anisatin Chemical Structure

Anisatin Chemical Structure

CAS No. : 5230-87-5

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规格 价格 是否有货 数量
1 mg ￥1977
In-stock
5 mg ￥4350
In-stock
10 mg ￥7800
In-stock
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Anisatin 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anisatin, a pure toxic substance isolated from the seeds of a Japanese plant (Illicium anisatum) acts as a picrotoxin-like, non-competitive GABA antagonist. Anisatin suppresses GABA-induced currents in a concentration-dependent manner with an EC50 of ~1.10 μM[1].

体外研究
(In Vitro)

Anisatin inhibits [3H]diazepam binding enhanced by either GABA or pentobarbital, without affecting the basal specific binding to rat brain membranes[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Anisatin 相关抗体:
体内研究
(In Vivo)

In mice, the LD50 reported for anisatin ranges from 0.76 to 1 mg/kg (po and ip)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

328.31

Formula

C15H20O8
CAS 号
性状

固体

颜色

White to off-white

中文名称

莽草毒素
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

纯度 & 产品资料

纯度: ≥98.0%

COA (279 KB)

产品使用指南 (1538 KB)
参考文献

Anisatin 相关分类

  • 摩尔计算器

  • 稀释计算器

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Keywords:

Anisatin5230-87-5莽草毒素GABA ReceptorGamma-aminobutyric acid Receptorγ-Aminobutyric acid Receptorpicrotoxindorsalrootganglionpatchclampsingle channelInhibitorinhibitorinhibit

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