2. Immunology/Inflammation
  3. Fc Receptor (FcR)
  4. Anti-CD32/FcγRIIA Antibody (IV.3)

Anti-CD32/FcγRIIA Antibody (IV.3) 

目录号: HY-P990863 纯度: ≥95.0%
COA 技术支持

Anti-CD32/FcγRIIA Antibody (IV.3) 是一种小鼠 IgG2b 嵌合抗体抑制剂，靶向人 CD32/FcγRIIA。Anti-CD32/FcγRIIA Antibody (IV.3) 能够阻断 Fc 受体 IIA。Anti-CD32/FcγRIIA Antibody (IV.3) 可用于炎症和感染的研究，如关节炎和大肠杆菌 (E. coli) 感染。

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Anti-CD32/FcγRIIA Antibody (IV.3)

Anti-CD32/FcγRIIA Antibody (IV.3) Chemical Structure

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1 mg ￥2200
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Anti-CD32/FcγRIIA Antibody (IV.3) 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anti-CD32/FcγRIIA Antibody (IV.3) is a kind of mouse IgG2b chimeric antibody inhibitor, targeting to human CD32/FcγRIIA. Anti-CD32/FcγRIIA Antibody (IV.3) can block Fc receptor IIA. Anti-CD32/FcγRIIA Antibody (IV.3) can be used for the researches of inflammation and infection, such as arthritis and E. coli infection[1][2].

同型

Mouse IgG2b
推荐同型对照抗体
反应种属

Human
IC50 & Target

CD32/FcγRIIA
体外研究
(In Vitro)

Anti-CD32/FcγRIIA Antibody (IV.3) (10 μg/mL, 30 mins) 会减少皮肤来源及体外生成的朗格汉斯细胞和真皮树突状细胞对金黄色葡萄球菌 (S. aureus) 或大肠杆菌 (E. coli) 的摄取[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Anti-CD32/FcγRIIA Antibody (IV.3) 相关抗体:
体内研究
(In Vivo)

Anti-CD32/FcγRIIA Antibody (IV.3) (F(ab′)2 片段) (1 mg/g，静脉注射，每 2 天一次) 可抑制胶原抗体诱导的关节炎 (CAIA) 模型的转基因 hFcγRIIA 小鼠中的关节炎发展[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Transgenic hFcγRIIA mice subjected to the collagen antibody-induced arthritis (CAIA) model[2]
Dosage: 1 mg/g
Administration: Intravenously injection, every 2 days
Result: Reduced ankle thickening.
Decreased the production of TNF-α, IL-6, and MIP-2.
基因 ID

2212  [NCBI]

Accession
应用

ELISA, FACS, Functional assay, Research in vivo
偶联物

Unconjugated
复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.
分子量

150 kDa

性状

液体

颜色

Colorless to light yellow

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

纯度: ≥95.0%

COA (268 KB)

抗体抑制剂使用指南 (1152 KB)
参考文献

Anti-CD32/FcγRIIA Antibody (IV.3) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-CD32/FcγRIIA Antibody (IV.3)Fc Receptor (FcR)Fc ReceptorCD32FcγRIIAFc receptorArthritisE. coliLangerhans cellsInhibitorinhibitorinhibit

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