2. Immunology/Inflammation
  3. Mesothelin
  4. Anti-Mesothelin Antibody (YP218)

Anti-Mesothelin Antibody (YP218) 

目录号: HY-P990833 纯度: 95.00%
COA 技术支持

Anti-Mesothelin Antibody (YP218) 是一种兔 IgG 嵌合抗体，靶向人 Mesothelin。Anti-Mesothelin Antibody (YP218) 与靠近肿瘤细胞表面的人源间皮素 (MSLN) 的 C 末端的一个表位发生反应。Anti-Mesothelin Antibody (YP218) 可用于癌症研究，如 A431/H9 肿瘤。

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Anti-Mesothelin Antibody (YP218)

Anti-Mesothelin Antibody (YP218) Chemical Structure

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1 mg ￥2200
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Anti-Mesothelin Antibody (YP218) 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anti-Mesothelin Antibody (YP218) is a kind of rabbit IgG chimeric antibody, targeting to human Mesothelin. Anti-Mesothelin Antibody (YP218) reacts with a epitope in the C-terminal end close to the tumor cell surface of human mesothelin (MSLN). Anti-Mesothelin Antibody (YP218) can be used for the research of cancer, such as A431/H9 tumor[1].

同型

Rabbit IgG
推荐同型对照抗体
反应种属

Human
IC50 & Target

Mesothelin
体外研究
(In Vitro)

Anti-Mesothelin Antibody (YP218) (人源化 YP218 与 IR700 结合物) (3 μg/mL, 6 h) 在 A431/H9 细胞中显示出高荧光信号[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Anti-Mesothelin Antibody (YP218) 相关抗体:
体内研究
(In Vivo)

Anti-Mesothelin Antibody (YP218) (人源化 YP218 与 IR700 结合物) (100 μg，静脉注射，单剂量) 联合近红外光免疫疗法 可抑制 A431/H9 肿瘤小鼠 (无胸腺裸鼠) 中的肿瘤生长[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: A431/H9 tumor mice (6-8 weeks, female homozygote athymic nude mice)[1]
Dosage: 100 μg (humanized YP218 and IR700 conjugation)
Administration: Intravenously injection
Result: Showed higher fluorescence intensity.
基因 ID

56047  [NCBI]

Accession
应用

ELISA, FACS, Functional assay, Research in vivo
偶联物

Unconjugated
复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.
分子量

150 kDa

性状

液体

颜色

Colorless to light yellow

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

纯度: 95.00%

COA (268 KB)

抗体抑制剂使用指南 (1152 KB)
参考文献

Anti-Mesothelin Antibody (YP218) 相关分类

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-Mesothelin Antibody (YP218)MesothelinMSLNA431/H9Inhibitorinhibitorinhibit

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Anti-Mesothelin Antibody (YP218)
目录号：
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