2. 抗体抑制剂
  3. 动物体内抗体
  4. Anti-Mouse CD200 Antibody (OX-90)

Anti-Mouse CD200 Antibody (OX-90) 

目录号: HY-P990285 纯度: 95.00%
COA 技术支持

Anti-Mouse CD200 Antibody (OX-90) 是一种抗小鼠 CD200 IgG2a 单克隆抗体。Anti-Mouse CD200 Antibody (OX-90) 可以通过阻断 CD200 来减少免疫细胞浸润和 T 细胞功能。Anti-Mouse CD200 Antibody (OX-90) 可用于免疫学研究。

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Anti-Mouse CD200 Antibody (OX-90)

Anti-Mouse CD200 Antibody (OX-90) Chemical Structure

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1 mg ￥2200
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Anti-Mouse CD200 Antibody (OX-90) 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anti-Mouse CD200 Antibody (OX-90) is an anti-mouse CD200 IgG2a monoclonal antibody. Anti-Mouse CD200 Antibody (OX-90) can reduce immune cell infiltration and T cell function by blocking CD200. Anti-Mouse CD200 Antibody (OX-90) can be used for research on immunology[1][2].

同型

Rat IgG2a kappa
推荐同型对照抗体
反应种属

Mouse
IC50 & Target

CD200
体内研究
(In Vivo)

Anti-Mouse CD200 Antibody (OX-90) (250 μg，腹腔注射，每 3 天一次，从第 7 天到第 18 天) 可减少携带 Yumm1.7 肿瘤的 C57BL/6 小鼠在肿瘤免疫微环境 (TIME) 中的免疫细胞浸润和 T 细胞功能[1]。
Anti-Mouse CD200 Antibody (OX-90) (200 μg，静脉注射，第 3、6、9、12 天) 可以减弱抗 PD-L1 单克隆抗体对携带 MC38 或 EG7 肿瘤的雌性 C57BL/6 小鼠的治疗作用[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 5×105 Yumm1.7 cells injected C57BL/6 mice[1]
Dosage: 250 μg
Administration: Intraperitoneal injection (i.p.), once every 3 days, from day 7 to day 18
Result: Reduced immune cells in tumors and upregulated CCL8 expression.
Animal Model: 5×105 MC38 or EG7 cells injected female C57BL/6 mice (6-8 weeks)[2]
Dosage: 200 μg
Administration: Intravenous injection (i.v.), on day 3, 6, 9,12
Result: Weakened the therapeutic effect of anti-PD-L1 mAb.
基因 ID

17470  [NCBI]

Accession
应用

ELISA, FACS, Functional assay, Research in vivo
偶联物

Unconjugated
复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.
分子量

150 kDa

性状

液体

颜色

Colorless to light yellow

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Anti-Mouse CD200 Antibody (OX-90) 相关分类

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-Mouse CD200 Antibody (OX-90)OthersCD200T cellMC38EG7Yumm1.7Inhibitorinhibitorinhibit

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