2. Metabolic Enzyme/Protease
  3. Phosphatase
  4. Anti-Mouse CD45.2 Antibody (104.2)

Anti-Mouse CD45.2 Antibody (104.2) 

目录号: HY-P990268
技术支持

Anti-Mouse CD45.2 Antibody (104.2) 是一种小鼠源性 IgG2a κ 型抗体抑制剂，靶向小鼠 CD45.2。Anti-Mouse CD45.2 Antibody (104.2) 可抑制 B 细胞分化。Anti-Mouse CD45.2 Antibody (104.2) 可用于炎症和免疫学研究，如脂多糖 (HY-D1056) 诱导的炎症和自身免疫。

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Anti-Mouse CD45.2 Antibody (104.2)

Anti-Mouse CD45.2 Antibody (104.2) Chemical Structure

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Anti-Mouse CD45.2 Antibody (104.2) 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anti-Mouse CD45.2 Antibody (104.2) is a mouse-derived IgG2a κ type antibody inhibitor, targeting to mouse CD45.2. Anti-Mouse CD45.2 Antibody (104.2) can inhibit B Cell differentiation. Anti-Mouse CD45.2 Antibody (104.2) can be used for the researches of inflammation and immunology, such as LPS (HY-D1056)-induced inflammation and autoimmunity[1][2][3].

同型

Mouse IgG2a kappa
推荐同型对照抗体
反应种属

Mouse
体外研究
(In Vitro)

Anti-Mouse CD45.2 Antibody (104.2) 抑制 B6 脾细胞产生抗绵羊红细胞的蚀斑形成细胞[3]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Anti-Mouse CD45.2 Antibody (104.2) 相关抗体:
体内研究
(In Vivo)

Anti-Mouse CD45.2 Antibody (104.2) (250 μg，腹腔注射， LPS 注射后 1 小时后给药) 可增强 LPS 诱导的炎症，并加快经 LPS (HY-D1056) 处理的 LgalsI−/− 小鼠的死亡速度[1]。
Anti-Mouse CD45.2 Antibody (104.2) (2 mg，静脉注射，在 5 周时给药两次，之后按 1 mg，腹腔注射，每周两次，直至 24 周) 可减轻 BXSB 雄性小鼠的自身免疫并降低死亡率[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: BXSB male mice[2]
Dosage: 2 mg, i.v., at 5 weeks and 1 mg, i.p., until 24 weeks
Administration: Twice a week
Result: Decreased mortality.
Showed mild proteinuria.
Reduced the severity of membranoproliferative glomerulonephritis.
应用

ELISA, FACS, Functional assay, Research in vivo
偶联物

Unconjugated
复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.
分子量

150 kDa

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Anti-Mouse CD45.2 Antibody (104.2) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-Mouse CD45.2 Antibody (104.2)PhosphataseCD45B cellsLPSSheep erythrocytesBXSBInhibitorinhibitorinhibit

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