2. Immunology/Inflammation
  3. CD73
  4. Anti-Mouse CD73 Antibody (TY/23)

Anti-Mouse CD73 Antibody (TY/23) 

目录号: HY-P990263 纯度: 95.00%
COA 技术支持

Anti-Mouse CD73 Antibody (TY/23) 是一种大鼠来源的 IgG2a κ 型抗体抑制剂，靶向小鼠 CD73。Anti-Mouse CD73 Antibody (TY/23) 可中和 CD73。Anti-Mouse CD73 Antibody (TY/23) 可用于癌症、感染和免疫学等方面的研究，如 B16F10 肿瘤和小鼠巨细胞病毒感染。

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Anti-Mouse CD73 Antibody (TY/23)

Anti-Mouse CD73 Antibody (TY/23) Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
1 mg ￥2000
In-stock
5 mg 现货 询价
10 mg 现货 询价
50 mg   询价  
100 mg   询价  

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Anti-Mouse CD73 Antibody (TY/23) 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anti-Mouse CD73 Antibody (TY/23) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse CD73. Anti-Mouse CD73 Antibody (TY/23) can neutralize CD73. Anti-Mouse CD73 Antibody (TY/23) can be used for the researches of cancer, infection and immunology, such as B16F10 tumor and murine cytomegalovirus infection[1][2].

同型

Rat IgG2a kappa
推荐同型对照抗体
反应种属

Mouse
IC50 & Target

CD73
体外研究
(In Vitro)

抗体框架具有稳定性、特异性和适应性，同时具有结合抗原和内源免疫受体。 单克隆抗体具有几种衍生物，包括双特异性抗体、抗体-药物缀合物和抗体片段，在免疫学和肿瘤学等领域具有显著效果。 设计抑制性抗体时，需要注意包括抗原特异性可变区的鉴定、表达系统的选择、多特异性形式的使用以及基于片段化、寡聚化或与其他功能部分缀合的抗体衍生物[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Anti-Mouse CD73 Antibody (TY/23) 相关抗体:
体内研究
(In Vivo)

Anti-Mouse CD73 Antibody (TY/23) (100 μg，腹腔注射，在第 3、7、10、14、17、21 和 24 天给药) 可抑制转基因 DEREG 小鼠模型中的 MC38-ova 肿瘤生长[1]。
Anti-Mouse CD73 Antibody (TY/23) (200 μg，静脉注射，在肿瘤接种前 1 天和 2 小时给药) 可抑制野生型小鼠 B16F10 肺转移瘤的形成[1]。
Anti-Mouse CD73 Antibody (TY/23) (200 μg，静脉注射，每两天一次，持续 2 周) 可改善鼠巨细胞病毒感染小鼠肾脏和脾脏中 OT-I T 细胞的功能[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: MC38-ova transgenic DEREG mice models[1]
Dosage: 100 μg
Administration: Intraperitoneally injection, at days 3, 7, 10, 14, 17, 21, and 24
Result: Inhibited tumor growth.
基因 ID

23959  [NCBI]

Accession
应用

ELISA, FACS, Functional assay, Research in vivo
偶联物

Unconjugated
复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.
分子量

150 kDa

性状

液体

颜色

Colorless to light yellow

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

纯度: 95.00%

COA (268 KB)

抗体抑制剂使用指南 (1152 KB)
参考文献

Anti-Mouse CD73 Antibody (TY/23) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-Mouse CD73 Antibody (TY/23)CD73ecto-5′-nucleotidase, NT5ECancerB16F10MC38-ovaMurine cytomegalovirusOT-I T cellsInhibitorinhibitorinhibit

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Anti-Mouse CD73 Antibody (TY/23)
目录号：
HY-P990263
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