2. Immunology/Inflammation
  3. Transmembrane Glycoprotein
  4. Anti-Mouse CD86/B7-2 Antibody (GL-1)

Anti-Mouse CD86/B7-2 Antibody (GL-1) 

目录号: HY-P990260 纯度: 99.17%
COA 技术支持

Anti-Mouse CD86/B7-2 Antibody (GL-1) 是一种源自大鼠的 IgG2a κ 型抗体抑制剂，靶向小鼠 CD86/B7-2。Anti-Mouse CD86/B7-2 Antibody (GL-1) 可用于炎症和免疫学研究，如过敏性肺炎。

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Anti-Mouse CD86/B7-2 Antibody (GL-1)

Anti-Mouse CD86/B7-2 Antibody (GL-1) Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
1 mg ￥560
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5 mg ￥2200
In-stock
10 mg ￥3600
In-stock
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100 mg   询价  

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Anti-Mouse CD86/B7-2 Antibody (GL-1) 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anti-Mouse CD86/B7-2 Antibody (GL-1) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse CD86/B7-2. Anti-Mouse CD86/B7-2 Antibody (GL-1) can be used for the researches of inflammation and immunology, such as allergic pulmonary inflammation[1][2][3][4].

同型

Rat IgG2a kappa
推荐同型对照抗体
反应种属

Mouse
IC50 & Target

CD86/B7-2
体外研究
(In Vitro)

Anti-Mouse CD86/B7-2 Antibody (GL-1) (7 days) 可诱导脾细胞中免疫调节细胞的产生[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Anti-Mouse CD86/B7-2 Antibody (GL-1) 相关抗体:
体内研究
(In Vivo)

Anti-Mouse CD86/B7-2 Antibody (GL-1) (100 μg，腹腔注射，单剂量) 可抑制实验性过敏性脑脊髓炎模型小鼠中 IL-2 分泌细胞的发育，并增强 TNF-α 的分泌[2]。
Anti-Mouse CD86/B7-2 Antibody (GL-1) (400 μg，腹腔注射，隔天一次，共 4 次) 可减轻卵清蛋白诱导的过敏性肺部炎症模型小鼠中的炎症反应[3]。
Anti-Mouse CD86/B7-2 Antibody (GL-1) (200 μg，腹腔注射，单剂量) 可延长心脏移植模型小鼠的存活时间[4]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Ovalbumin-induced allergic pulmonary inflammation mice models[3]
Dosage: 400 μg
Administration: Intraperitoneally injection (the first doses via tail vein), every other day for 4 times
Result: Decreased expression of CD25 on CD4+ T cells.
Decreased allergen-induced AHR and the expansion of eosinophil subset in the BAL.
Showed slightly attenuated inflammation.
Animal Model: Cardiac allografts mice models[4]
Dosage: 200 μg
Administration: Intraperitoneally injection
Result: Led to more than 2 months allograft survival in all mice.
基因 ID

12524  [NCBI]

Accession
应用

ELISA, FACS, Functional assay, Research in vivo
偶联物

Unconjugated
复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.
分子量

150 kDa

性状

液体

颜色

Colorless to light yellow

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Anti-Mouse CD86/B7-2 Antibody (GL-1) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-Mouse CD86/B7-2 Antibody (GL-1)Transmembrane GlycoproteinCD86B7-2Allergic pulmonary inflammationExperimental allergic encephalomyelitisOvalbuminInhibitorinhibitorinhibit

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